Vol. 27 (1-2) 2006 Neuro endocrinology letters

Microdialysis measurement of acetylcholine in rat hippocampus during severe insulin-induced hypoglycemia.

OBJECTIVE: It has been well acknowledged that hypoglycemia induces cognitive impairment. However, the behavior of hippocampal cholinergic system, which is thought to play a key role in cognition, during hypoglycemia remains to be elucidated.

MATERIALS AND METHODS: In this study we conducted a microdialysis using .....