Distinct lethal arrhythmias susceptibility is associated with sex-related difference in myocardial connexin-43 expression.
OBJECTIVES: To elucidate gender-related differences in occurrence of sudden cardiac death the myocardial connexin-43 (Cx43) and the susceptibility of male and female rat hearts to ventricular fibrillation (VF) were investigated.
METHODS AND RESULTS: Ventricular tissues taken from male and female normotensive Wist.....