Vol. 29 (5) 2008 Neuro endocrinology letters

Distinct lethal arrhythmias susceptibility is associated with sex-related difference in myocardial connexin-43 expression.

OBJECTIVES: To elucidate gender-related differences in occurrence of sudden cardiac death the myocardial connexin-43 (Cx43) and the susceptibility of male and female rat hearts to ventricular fibrillation (VF) were investigated.

METHODS AND RESULTS: Ventricular tissues taken from male and female normotensive Wist.....