Vol. 29 (5) 2008 Neuro endocrinology letters

The effect of HI-6 on cholinesterases and on the cholinergic system of the rat bladder.

OBJECTIVES: The current standard treatment of organophosphate poisoning consists of an administration of anticholinergic drugs and cholinesterase reactivators (oximes). Oximes can react - except their reactivating effect on cholinesterases - directly with cholinoreceptors. HI-6 is an oxime that may have an inhibitory effect on the musca.....