ISSN: 0172-780X | ISSN-L: 0172-780X | eISSN 2354-4716

www.nel.edu Editor-in-Chief: Peter G. Fedor-Freybergh

Neuro endo. lett. - 2008

Vol. 29 (5) 2008 Neuro endocrinology letters

The use of melatonin to combat mustard toxicity. REVIEW.

Korkmaz A, Kunak Z, Paredes S, Yaren H, Tan D, Reiter R.

Journal Article 2008; 29(5): 614-619 PubMed PMID: 18987575 Keywords: Animals, Antioxidants:pharmacology, Bioterrorism, Chemical Warfare Agents:toxicity, Humans, Melatonin:pharmacology, Mustard Gas:toxicity, Neurotoxicity Syndromes:prevention & control,.

: Among the most readily available chemical warfare agents, sulfur mustard (SM) has been the most widely used chemical weapon. The toxicity of SM as an incapacitating agent is of much greater importance than its ability to cause lethality. Oxidative stress is the first and key event in the pathogenesis of SM toxicity. The involvement of.....

A one-electron oxidation of carcinogenic nonaminoazo dye Sudan I by horseradish peroxidase.

Semanska M, Dracinsky M, Martinek V, Hudecek J, Hodek P, Frei E, Stiborova M.

Journal Article 2008; 29(5): 712-716 PubMed PMID: 18987613 Keywords: Carcinogens:chemistry, Chromatography, High Pressure Liquid, Chromatography, Thin Layer, Electrons, Horseradish Peroxidase:chemistry, Hydrogen Peroxide:chemistry, Magnetic Resonance Spectroscopy, Mass Spectrometry, Naphthols:chemistry, Oxidation-Reduction.

Read abstract Full text PDF

Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production.

Konopka R, Kubala L, Lojek A, Pacherník J.

Journal Article 2008; 29(5): 770-774 PubMed PMID: 18987612 Keywords: Acetophenones:pharmacology, Acetylcysteine:pharmacology, Ascorbic Acid:pharmacology, Blotting, Western, Cell Differentiation:drug effects, Embryonal Carcinoma Stem Cells:drug effects, Flow Cytometry, Free Radical Scavengers:pharmacology, Genes, Reporter:d.

Read abstract Full text PDF

An alternative management for growth retarded fetus with absent end-diastolic velocity in umbilical artery and normal cardiotocography.

Ferianec V, Redecha M, Brucknerova I, Holly I, Holoman K.

Case Reports 2008; 29(5): 635-638 PubMed PMID: 18987611 Keywords: Adult, Amniocentesis, Blood Gas Analysis, Cordocentesis, Echocardiography, Electrocardiography, Female, Fetal Growth Retardation:diagnostic imaging, Heart Rate:physiology, Heart Rate, Fetal:physiology, Humans, Hypoxia:etiology, Infant, Newborn, Infant, Pr.

Read abstract Full text PDF

Biliary 1-hydroxypyrene as a biomarker of exposure to polycyclic aromatic hydrocarbons in fish.

Blahova J, Kruzikova K, Hilscherova K, Grabic R, Halirova J, Jurcikova J, Ocelka T, Svobodova Z.

Journal Article 2008; 29(5): 663-668 PubMed PMID: 18987610 Keywords: Animals, Bile:metabolism, Biomarkers, Chromatography, High Pressure Liquid, Cyprinidae:physiology, Czech Republic, Environmental Monitoring, Fishes:metabolism, Fresh Water, Mutagens:metabolism, Polycyclic Aromatic Hydrocarbons:analysis, Proteins:metabolis.

Read abstract Full text PDF

Chromosomal damage and polymorphisms of DNA repair genes XRCC1 and XRCC3 in workers exposed to chromium.

Halasova E, Matakova T, Musak L, Polakova V, Vodicka P.

Journal Article 2008; 29(5): 658-662 PubMed PMID: 18987609 Keywords: Aged, Chromium:blood, Chromosome Breakage:drug effects, DNA Repair:genetics, DNA-Binding Proteins:drug effects, Humans, Male, Metallurgy, Middle Aged, Occupational Exposure:adverse effects, Polymorphism, Genetic:drug effects,.

Read abstract Full text PDF

Chronic low-dose L-NAME treatment effect on cardiovascular system of borderline hypertensive rats: feedback regulation?

Kopincova J, Puzserova A, Bernatova I.

Journal Article 2008; 29(5): 784-789 PubMed PMID: 18987608 Keywords: Acetylcholine:metabolism, Animals, Blood Pressure:drug effects, Body Weight:drug effects, Cardiovascular Physiological Phenomena:drug effects, Enzyme Inhibitors:pharmacology, Feedback, Physiological:drug effects, Hypertension:drug therapy, Isometric Contr.

Read abstract Full text PDF

Comparison of acute toxicity of 2-phenoxyethanol and clove oil to juvenile and embryonic stages of Danio rerio.

Macova S, Dolezelova P, Pistekova V, Svobodova Z, Bedanova I, Voslarova E.

Comparative Study 2008; 29(5): 680-684 PubMed PMID: 18987607 Keywords: Anesthetics:toxicity, Animals, Clove Oil:toxicity, Ethylene Glycols:toxicity, Larva, Lethal Dose 50, Plant Oils:toxicity, Syzygium:toxicity, Temperature, Zebrafish:physiology,.

Read abstract Full text PDF

Distinct lethal arrhythmias susceptibility is associated with sex-related difference in myocardial connexin-43 expression.

Knezl V, Bacova B, Kolenova L, Mitasikova M, Weismann P, Drimal J, Tribulova N.

Journal Article 2008; 29(5): 798-801 PubMed PMID: 18987606 Keywords: Animals, Arrhythmias, Cardiac:genetics, Connexin 43:biosynthesis, Connexins:metabolism, Electrocardiography, Female, Immunohistochemistry, Male, Microscopy, Fluorescence, Myocardium:metabolism, Rats, Rats, Inbred SHR, Rats, Wistar, Sex Characteristics,.

Read abstract Full text PDF

Drugs during lactation accenting boron exposure.

Manakova E, Hubickova-Heringova L, Novakova L.

Journal Article 2008; 29(5): 631-634 PubMed PMID: 18987605 Keywords: Adult, Anti-Infective Agents, Local:adverse effects, Anticonvulsants:adverse effects, Biological Availability, Boric Acids:adverse effects, Breast Feeding:adverse effects, Czech Republic, Drug Information Services:statistics & numerical data, Drug-Related.

Read abstract Full text PDF

Effect of carvedilol on the production of reactive oxygen species by HL-60 cells.

Lojek A, Pecivova J, Macickova T, Nosal R, Papezikova I, Ciz M.

Journal Article 2008; 29(5): 779-783 PubMed PMID: 18987604 Keywords: Adenosine Triphosphate:metabolism, Adrenergic beta-Antagonists:pharmacology, Carbazoles:pharmacology, Cell Differentiation:drug effects, Cell Proliferation:drug effects, Fluorometry, Granulocytes:drug effects, HL-60 Cells, Humans, Luminescence, Nitric Oxi.

Read abstract Full text PDF

Effect of the extract from salivary glands of Lucilia sericata on human neutrophils.

Pecivova J, Macickova T, Takac P, Kovacsova M, Cupanikova D, Kozanek M.

Journal Article 2008; 29(5): 794-797 PubMed PMID: 18987603 Keywords: Animals, Diptera:physiology, Humans, Larva, Luminescence, Male, Neutrophils:drug effects, Peroxidase:metabolism, Salivary Glands:physiology, Superoxides:metabolism, Tissue Extracts:pharmacology, Zymosan,.

Read abstract Full text PDF

Effect of transient ischemia on long-term potentiation of synaptic transmission in rat hippocampal slices.

Gasparova Z, Jariabka P, Stolc S.

Journal Article 2008; 29(5): 702-705 PubMed PMID: 18987602 Keywords: Animals, Electric Stimulation, Excitatory Postsynaptic Potentials:physiology, Hippocampus:blood supply, Ischemic Attack, Transient:physiopathology, Long-Term Potentiation:physiology, Male, Rats, Rats, Wistar, Synaptic Transmission:physiology,.

Read abstract Full text PDF

Effects of subchronic metribuzin exposure on common carp (Cyprinus carpio).

Modra H, Haluzova I, Blahova J, Havelkova M, Kruzikova K, Mikula P, Svobodova Z.

Journal Article 2008; 29(5): 669-674 PubMed PMID: 18987601 Keywords: Animals, Blood Cell Count, Carps:physiology, Cytochrome P-450 CYP1A1:metabolism, Cytochrome P-450 Enzyme System:metabolism, Erythrocyte Count, Herbicides:toxicity, Liver:drug effects, Triazines:toxicity, Vitellogenesis:drug effects, Water Pollutants, Chem.

Read abstract Full text PDF

Evaluation of genotoxic and cytotoxic effects of H2O2 and DMNQ on freshly isolated rat hepatocytes; protective effects of carboxymethyl chitin-glucan.

Horvathova E, Eckl P, Bresgen N, Slamenova D.

Journal Article 2008; 29(5): 644-648 PubMed PMID: 18987600 Keywords: Animals, Antioxidants, Apoptosis:drug effects, Cell Count, Cell Death, Cell Separation, Chitin:analogs & derivatives, Comet Assay, DNA:drug effects, DNA Damage:drug effects, Female, Glucans:pharmacology, Hepatocytes:drug effects, Hydrogen Peroxide:toxicit.

Read abstract Full text PDF

Glucomannan in prevention of oxidative stress and inflammation occurring in adjuvant arthritis.

Bauerova K, Ponist S, Navarova J, Dubnickova M, Paulovicova E, Pajtinka M, Kogan G, Mihalova D.

Journal Article 2008; 29(5): 691-696 PubMed PMID: 18987599 Keywords: Animals, Anti-Inflammatory Agents, Non-Steroidal, Antioxidants:metabolism, Arthritis, Experimental:pathology, Candida:chemistry, Foot:pathology, Inflammation:pathology, Male, Mannans:pharmacology, Mycobacterium:immunology, Oxidative Stress:drug effects, P.

Read abstract Full text PDF

Human cytochromes P450 1A1 and 1A2 participate in detoxication of carcinogenic aristolochic acid.

Sistkova J, Hudecek J, Hodek P, Frei E, Schmeiser H, Stiborova M.

Journal Article 2008; 29(5): 733-737 PubMed PMID: 18987598 Keywords: Animals, Aristolochic Acids:pharmacokinetics, Carcinogens:pharmacokinetics, Chromatography, High Pressure Liquid, Cytochrome P-450 CYP1A1:isolation & purification, Cytochrome P-450 CYP1A2:isolation & purification, Humans, Inactivation, Metabolic, Mice, Mi.

Read abstract Full text PDF

Hyaluronan influence on the onset of chondrogenic differentiation of mesenchymal stem cells.

Dvorakova J, Velebny V, Kubala L.

Journal Article 2008; 29(5): 685-690 PubMed PMID: 18987597 Keywords: Cartilage:cytology, Cell Differentiation:drug effects, Chondrocytes:drug effects, Collagen Type II:biosynthesis, Collagen Type XI:biosynthesis, Extracellular Matrix:drug effects, Gene Expression:drug effects, Glycosaminoglycans:metabolism, Humans, Hyaluro.

Read abstract Full text PDF

Induction of cytochromes P450 in small intestine by chemopreventive compounds.

Krizkova J, Burdova K, Hudecek J, Stiborova M, Hodek P.

Journal Article 2008; 29(5): 717-721 PubMed PMID: 18987596 Keywords: Allyl Compounds:pharmacology, Animals, Anticarcinogenic Agents:pharmacology, Blotting, Western, Curcumin:pharmacology, Cytochrome P-450 CYP1A1:biosynthesis, Cytochrome P-450 CYP2B1:biosynthesis, Cytochrome P-450 Enzyme System:biosynthesis, Flavonoids:phar.

Read abstract Full text PDF

Inhibition of superoxide generation and myeloperoxidase release by carvedilol after receptor and nonreceptor stimulation of human neutrophils.

Macickova T, Pecivova J, Nosal R, Lojek A, Pekarova M, Cupanikova D.

Journal Article 2008; 29(5): 790-793 PubMed PMID: 18987595 Keywords: Adrenergic beta-Antagonists:pharmacology, Androstadienes:pharmacology, Calcimycin:pharmacology, Carbazoles:pharmacology, Humans, In Vitro Techniques, Male, N-Formylmethionine Leucyl-Phenylalanine:pharmacology, Neutrophils:drug effects, Oxidants:metabolism.

Read abstract Full text PDF

Interspecies comparison of the glucuronidation processes in the man, monkey, pig, dog and rat.

Matal J, Jancova P, Siller M, Masek V, Anzenbacherova E, Anzenbacher P.

Comparative Study 2008; 29(5): 738-743 PubMed PMID: 18987594 Keywords: Animals, Dogs, Glucuronides:metabolism, Glucuronosyltransferase:metabolism, Haplorhini, Humans, Kinetics, Microsomes, Liver:enzymology, Protective Agents:metabolism, Rats, Silymarin:metabolism, Species Specificity, Swine,.

Read abstract Full text PDF

Isolation and identification of the Amanita muscaria and Amanita pantherina toxins in human urine.

Merova B, Ondra P, Stankova M, Valka I.

Journal Article 2008; 29(5): 744-748 PubMed PMID: 18987593 Keywords: Amanita:chemistry, Amanitins:urine, Chromatography, High Pressure Liquid, Humans, Ibotenic Acid:urine, Indicators and Reagents, Muscarine:urine, Muscimol:urine, Nucleic Acid Synthesis Inhibitors:urine, Solid Phase Extraction, Solvents, Spectrometry, Mass,.

Read abstract Full text PDF

Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA.

Moserova M, Kotrbova V, Rupertova M, Naiman K, Hudecek J, Hodek P, Frei E, Stiborova M.

Journal Article 2008; 29(5): 728-732 PubMed PMID: 18987592 Keywords: Acetyl Coenzyme A:metabolism, Arylamine N-Acetyltransferase:metabolism, Arylsulfotransferase:metabolism, Autoradiography, Catalysis, DNA:chemistry, DNA Adducts:chemistry, Deoxyguanosine:chemistry, Ellipticines:chemistry, Hydrogen-Ion Concentration, Indica.

Read abstract Full text PDF

Mercury in human hair as an indicator of the fish consumption.

Kruzikova K, Modra H, Kensova R, Skocovska B, Wlasow T, Svoboda T, Svobodova Z.

Journal Article 2008; 29(5): 675-679 PubMed PMID: 18987591 Keywords: Adolescent, Age Factors, Animals, Child, Czech Republic:epidemiology, Dental Amalgam, Dental Restoration, Permanent, Diet, Female, Fishes:metabolism, Hair:chemistry, Humans, Male, Meat, Mercury:analysis, Poland:epidemiology, Sex Factors,.

Read abstract Full text PDF

New performance of biosensor technology for Alzheimer's disease drugs: in vitro comparison of tacrine and 7-methoxytacrine.

Pohanka M, Kuca K, Kassa J.

Comparative Study 2008; 29(5): 755-758 PubMed PMID: 18987590 Keywords: Acetylcholinesterase:chemistry, Algorithms, Alzheimer Disease:drug therapy, Biosensing Techniques, Cholinesterase Inhibitors:analysis, Electrochemistry, Enzymes, Immobilized:chemistry, Humans, Kinetics, Nootropic Agents:analysis, Tacrine:analogs & derivat.

Read abstract Full text PDF

Oxidative impairment of plasma and skeletal muscle sarcoplasmic reticulum in rats with adjuvant arthritis - effects of pyridoindole antioxidants.

Strosova M, Tomaskova I, Ponist S, Bauerova K, Karlovska J, Spickett C, Horakova L.

Journal Article 2008; 29(5): 706-711 PubMed PMID: 18987589 Keywords: Animals, Antioxidants:therapeutic use, Arthritis, Experimental:blood, Chromatography, High Pressure Liquid, Enzyme-Linked Immunosorbent Assay, Indoles:therapeutic use, Lipid Peroxidation:drug effects, Male, Mass Spectrometry, Muscle, Skeletal:drug effects.

Read abstract Full text PDF

Potential antioxidant activity, cytotoxic and apoptosis-inducing effects of Chelidonium majus L. extract on leukemia cells.

Nadova S, Miadokova E, Alfoldiova L, Kopaskova M, Hasplova K, Hudecova A, Vaculcikova D, Gregan F, Cipak L.

Journal Article 2008; 29(5): 649-652 PubMed PMID: 18987588 Keywords: Animals, Antineoplastic Agents, Phytogenic:pharmacology, Antioxidants:pharmacology, Apoptosis:drug effects, Biphenyl Compounds, Chelidonium:chemistry, Dose-Response Relationship, Drug, Free Radical Scavengers, HL-60 Cells, Humans, Leukemia:drug therapy, L.

Read abstract Full text PDF

Prenatal developmental toxicity study of the pyridoindole antioxidant SMe1EC2 in rats.

Ujhazy E, Dubovicky M, Ponechalova V, Navarova J, Brucknerova I, Snirc V, Mach M.

Journal Article 2008; 29(5): 639-643 PubMed PMID: 18987587 Keywords: Abnormalities, Drug-Induced:pathology, Animals, Antioxidants:toxicity, Female, Fetal Development:drug effects, Fetal Diseases:chemically induced, Indoles:toxicity, Neuroprotective Agents:toxicity, Pregnancy, Pyridines:toxicity, Rats, Rats, Wistar, Reprodu.

Read abstract Full text PDF

Reversible asphyxial status in a newborn due to neonatal form of carnitine palmitoyltransferase II deficiency.

Brucknerova I, Bzduch V, Behulova D, Ferianec V, Dubovicky M, Ujhazy E, Mach M.

Case Reports 2008; 29(5): 627-630 PubMed PMID: 18987586 Keywords: Asphyxia Neonatorum:enzymology, Cardiopulmonary Resuscitation, Carnitine O-Palmitoyltransferase:deficiency, Heart Failure:etiology, Humans, Infant, Newborn, Male, Respiratory Insufficiency:etiology, Tandem Mass Spectrometry,.

Read abstract Full text PDF

Melatonin reduces oxidative/nitrosative stress due to drugs, toxins, metals, and herbicides.

Reiter R, Korkmaz A, Paredes S, Manchester L, Tan D.

Journal Article 2008; 29(5): 609-613 PubMed PMID: 18987585 Keywords: Animals, Antioxidants:pharmacology, Drug-Related Side Effects and Adverse Reactions, Herbicides:toxicity, Humans, Melatonin:pharmacology, Metals:toxicity, Neurotoxins:toxicity, Oxidative Stress:drug effects, Prescription Drugs:toxicity, Reactive Nitrogen .

Read abstract Full text PDF

Nongenomic memory of foetal history in chronic diseases development.

Bezek S, Ujhazy E, Dubovicky M, Mach M.

Journal Article 2008; 29(5): 620-626 PubMed PMID: 18987584 Keywords: Adult, Animals, Chronic Disease:epidemiology, Environment, Female, Fetal Development:genetics, Fetus:physiology, Humans, Pregnancy, Young Adult,.

Read abstract Full text PDF

Perfluorinated compounds: occurrence and risk profile.

Kovarova J, Svobodova Z.

Journal Article 2008; 29(5): 599-608 PubMed PMID: 18987583 Keywords: Animals, Animals, Wild, Ecosystem, Environmental Pollutants:analysis, Fluorocarbons:analysis, Fresh Water, Humans, Risk Assessment,.

Read abstract Full text PDF

Screening and semiquantitative analysis of drugs and drugs of abuse in human serum samples using gas chromatography-mass spectrometry.

Maresova V, Chadt J, Novakova E.

Journal Article 2008; 29(5): 749-754 PubMed PMID: 18987582 Keywords: Acetamides, Calibration, Fluoroacetates, Gas Chromatography-Mass Spectrometry, Humans, Pharmaceutical Preparations:blood, Reproducibility of Results, Solid Phase Extraction, Substance Abuse Detection:methods, Substance-Related Disorders:blood, Trifluoroac.

Read abstract Full text PDF

Structural analysis of binding of a diamantoid substrate to cytochrome P450 2B4: possible role of Arg 133 in modulation of function and activity of this enzyme.

Sulc M, Hudecek J, Stiborova M, Hodek P.

Journal Article 2008; 29(5): 722-727 PubMed PMID: 18987581 Keywords: Adamantane:analogs & derivatives, Amino Acid Sequence, Animals, Arginine:genetics, Aryl Hydrocarbon Hydroxylases:antagonists & inhibitors, Chromatography, High Pressure Liquid, Crystallography, X-Ray, Cytochrome P450 Family 2, Enzyme Inhibitors:pharmacolo.

Read abstract Full text PDF

Structure-efficiency relationship in derivatives of stilbene. Comparison of resveratrol, pinosylvin and pterostilbene.

Perecko T, Jancinova V, Drabikova K, Nosal R, Harmatha J.

Journal Article 2008; 29(5): 802-805 PubMed PMID: 18987580 Keywords: Adenosine Triphosphate:metabolism, Antioxidants:pharmacology, Cell Survival:drug effects, Dose-Response Relationship, Drug, Humans, Luminescence, Neutrophils:drug effects, Reactive Oxygen Species:metabolism, Stilbenes:pharmacology, Structure-Activity Rela.

Read abstract Full text PDF

Study of pro- and anti-oxidative properties of D-penicillamine in a system comprising high-molar-mass hyaluronan, ascorbate, and cupric ions.

Valachova K, Hrabarova E, Gemeiner P, Soltes L.

Journal Article 2008; 29(5): 697-701 PubMed PMID: 18987579 Keywords: Antioxidants:chemistry, Ascorbic Acid:chemistry, Carbohydrate Sequence, Copper:chemistry, Free Radicals:chemistry, Hyaluronic Acid:chemistry, Hydrogen Peroxide:chemistry, Hydroxyl Radical:chemistry, Kinetics, Molecular Weight, Oxidants:chemistry, Penicill.

Read abstract Full text PDF

The effect of aldose reductase inhibition by JMC-2004 on hyperglycemia-induced endothelial dysfunction.

Papezikova I, Pekarova M, Chatzopoulou M, Nicolaou I, Demopoulos V, Kubala L, Lojek A.

Journal Article 2008; 29(5): 775-778 PubMed PMID: 18987578 Keywords: Aldehyde Reductase:antagonists & inhibitors, Animals, Blotting, Western, Calcimycin:pharmacology, Cattle, Cell Line, Electrochemistry, Endothelial Cells:drug effects, Endothelium, Vascular:drug effects, Enzyme Inhibitors:pharmacology, Glucose:pharmacology.

Read abstract Full text PDF

The effect of HI-6 on cholinesterases and on the cholinergic system of the rat bladder.

Soukup O, Pohanka M, Tobin G, Jun D, Fusek J, Musilek K, Marek J, Kassa J, Kuca K.

Journal Article 2008; 29(5): 759-762 PubMed PMID: 18987577 Keywords: Acetylcholinesterase:metabolism, Animals, Biosensing Techniques, Butyrylcholinesterase:metabolism, Cholinesterase Inhibitors:pharmacology, Methacholine Chloride:pharmacology, Muscarinic Agonists:pharmacology, Oximes, Parasympathetic Nervous System:drug ef.

Read abstract Full text PDF

The spectrum of the APC pathogenic mutations in Slovak FAP patients.

Matelova L, Stevurkova V, Zajac V.

Journal Article 2008; 29(5): 653-657 PubMed PMID: 18987576 Keywords: Adenomatous Polyposis Coli:epidemiology, Adenomatous Polyposis Coli Protein:genetics, Chromatography, High Pressure Liquid, DNA:biosynthesis, Gene Deletion, Mutation, Polymorphism, Single-Stranded Conformational:genetics, Reverse Transcriptase Polymerase .

Read abstract Full text PDF

The use of wireless capsule enteroscopy in a preclinical study: a novel diagnostic tool for indomethacin-induced gastrointestinal injury in experimental pigs.

Kvetina J, Kunes M, Bures J, Kopacova M, Tachecí I, Spelda S, Herout V, Rejchrt S.

Journal Article 2008; 29(5): 763-769 PubMed PMID: 18987574 Keywords: Animals, Anti-Inflammatory Agents, Non-Steroidal:toxicity, Capsule Endoscopy:methods, Female, Gastric Mucosa:pathology, Gastroscopy, Indomethacin:toxicity, Intestinal Mucosa:pathology, Microscopy, Confocal, Peptic Ulcer:chemically induced, Swine,.

Read abstract Full text PDF