Vol. 28 (6) 2007 Neuro endocrinology letters

Effects of the atypical antipsychotic clozapine on insulin release in vitro.

OBJECTIVES: Treatment with the atypical antipsychotic clozapine is frequently associated with metabolic side-effects such as weight gain, lipid abnormalities and diabetes mellitus. Since insulin is a hormone that is involved in both the regulation of body weight, as well as in lipid metabolism and glucose regulation, an effect of clozap.....