Why fish oils may not always be adequate treatments for depression or other inflammatory illnesses: docosahexaenoic acid, an omega-3 polyunsaturated fatty acid, induces a Th-1-like immune response.

Maes M, Mihaylova I, Kubera M, Bosmans E.

Comparative Study 2007; 28(6): 875-880 PubMed PMID: 18063921 Keywords: Adult, Analysis of Variance, Arachidonic Acid:administration & dosage, Cytokines:immunology, Depression:drug therapy, Docosahexaenoic Acids:administration & dosage, Dose-Response Relationship, Drug, Eicosapentaenoic Acid:administration & dosage, Female, H.

BACKGROUND: We have shown that a depletion of omega3 polysaturated fatty acids (PUFAs) plays a role in the pathophysiology of depression, in part because omega3 PUFAs have anti-inflammatory effects. omega3 PUFAs are frequently employed to treat depression. Most if not all antidepressants have negative immunoregulatory effects by decreas.....

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Vol. 28 (6) 2007 Neuro endocrinology letters

Why fish oils may not always be adequate treatments for depression or other inflammatory illnesses: docosahexaenoic acid, an omega-3 polyunsaturated fatty acid, induces a Th-1-like immune response.

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