Vol. 29 (5) 2008 Neuro endocrinology letters

The spectrum of the APC pathogenic mutations in Slovak FAP patients.

OBJECTIVES: The adenomatous polyposis coli (APC) gene was analyzed for germline mutations in 113 familial adenomatous polyposis suspected families from all over Slovakia. Mutation screening was performed using single strand conformation polymorphism (SSCP) and DNA sequencing.

RESULTS: Mutations in the APC gene we.....