Vol. 29 (5) 2008 Neuro endocrinology letters

The spectrum of the APC pathogenic mutations in Slovak FAP patients.

Matelova L, Stevurkova V, Zajac V.

Journal Article 2008; 29(5): 653-657 PubMed PMID: 18987576 Citation  Keywords:  Adenomatous Polyposis Coli:epidemiology, Adenomatous Polyposis Coli Protein:genetics, Chromatography, High Pressure Liquid, DNA:biosynthesis, Gene Deletion, Mutation, Polymorphism, Single-Stranded Conformational:genetics, Reverse Transcriptase Polymerase .

OBJECTIVES: The adenomatous polyposis coli (APC) gene was analyzed for germline mutations in 113 familial adenomatous polyposis suspected families from all over Slovakia. Mutation screening was performed using single strand conformation polymorphism (SSCP) and DNA sequencing.

RESULTS: Mutations in the APC gene we.....

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A one-electron oxidation of carcinogenic nonaminoazo dye Sudan I by horseradish peroxidase.

Semanska M, Dracinsky M, Martinek V, Hudecek J, Hodek P, Frei E, Stiborova M.
Journal Article 2008; 29(5): 712-716 PubMed PMID: 18987613 Citation  Keywords:  Carcinogens:chemistry, Chromatography, High Pressure Liquid, Chromatography, Thin Layer, Electrons, Horseradish Peroxidase:chemistry, Hydrogen Peroxide:chemistry, Magnetic Resonance Spectroscopy, Mass Spectrometry, Naphthols:chemistry, Oxidation-Reduction.

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Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production.

Konopka R, Kubala L, Lojek A, Pacherník J.
Journal Article 2008; 29(5): 770-774 PubMed PMID: 18987612 Citation  Keywords:  Acetophenones:pharmacology, Acetylcysteine:pharmacology, Ascorbic Acid:pharmacology, Blotting, Western, Cell Differentiation:drug effects, Embryonal Carcinoma Stem Cells:drug effects, Flow Cytometry, Free Radical Scavengers:pharmacology, Genes, Reporter:d.

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An alternative management for growth retarded fetus with absent end-diastolic velocity in umbilical artery and normal cardiotocography.

Ferianec V, Redecha M, Brucknerova I, Holly I, Holoman K.
Case Reports 2008; 29(5): 635-638 PubMed PMID: 18987611 Citation  Keywords:  Adult, Amniocentesis, Blood Gas Analysis, Cordocentesis, Echocardiography, Electrocardiography, Female, Fetal Growth Retardation:diagnostic imaging, Heart Rate:physiology, Heart Rate, Fetal:physiology, Humans, Hypoxia:etiology, Infant, Newborn, Infant, Pr.

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Biliary 1-hydroxypyrene as a biomarker of exposure to polycyclic aromatic hydrocarbons in fish.

Blahova J, Kruzikova K, Hilscherova K, Grabic R, Halirova J, Jurcikova J, Ocelka T, Svobodova Z.
Journal Article 2008; 29(5): 663-668 PubMed PMID: 18987610 Citation  Keywords:  Animals, Bile:metabolism, Biomarkers, Chromatography, High Pressure Liquid, Cyprinidae:physiology, Czech Republic, Environmental Monitoring, Fishes:metabolism, Fresh Water, Mutagens:metabolism, Polycyclic Aromatic Hydrocarbons:analysis, Proteins:metabolis.

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Chromosomal damage and polymorphisms of DNA repair genes XRCC1 and XRCC3 in workers exposed to chromium.

Halasova E, Matakova T, Musak L, Polakova V, Vodicka P.
Journal Article 2008; 29(5): 658-662 PubMed PMID: 18987609 Citation  Keywords:  Aged, Chromium:blood, Chromosome Breakage:drug effects, DNA Repair:genetics, DNA-Binding Proteins:drug effects, Humans, Male, Metallurgy, Middle Aged, Occupational Exposure:adverse effects, Polymorphism, Genetic:drug effects,.

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Chronic low-dose L-NAME treatment effect on cardiovascular system of borderline hypertensive rats: feedback regulation?

Kopincova J, Puzserova A, Bernatova I.
Journal Article 2008; 29(5): 784-789 PubMed PMID: 18987608 Citation  Keywords:  Acetylcholine:metabolism, Animals, Blood Pressure:drug effects, Body Weight:drug effects, Cardiovascular Physiological Phenomena:drug effects, Enzyme Inhibitors:pharmacology, Feedback, Physiological:drug effects, Hypertension:drug therapy, Isometric Contr.

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Distinct lethal arrhythmias susceptibility is associated with sex-related difference in myocardial connexin-43 expression.

Knezl V, Bacova B, Kolenova L, Mitasikova M, Weismann P, Drimal J, Tribulova N.
Journal Article 2008; 29(5): 798-801 PubMed PMID: 18987606 Citation  Keywords:  Animals, Arrhythmias, Cardiac:genetics, Connexin 43:biosynthesis, Connexins:metabolism, Electrocardiography, Female, Immunohistochemistry, Male, Microscopy, Fluorescence, Myocardium:metabolism, Rats, Rats, Inbred SHR, Rats, Wistar, Sex Characteristics,.

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Effect of carvedilol on the production of reactive oxygen species by HL-60 cells.

Lojek A, Pecivova J, Macickova T, Nosal R, Papezikova I, Ciz M.
Journal Article 2008; 29(5): 779-783 PubMed PMID: 18987604 Citation  Keywords:  Adenosine Triphosphate:metabolism, Adrenergic beta-Antagonists:pharmacology, Carbazoles:pharmacology, Cell Differentiation:drug effects, Cell Proliferation:drug effects, Fluorometry, Granulocytes:drug effects, HL-60 Cells, Humans, Luminescence, Nitric Oxi.

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Effects of subchronic metribuzin exposure on common carp (Cyprinus carpio).

Modra H, Haluzova I, Blahova J, Havelkova M, Kruzikova K, Mikula P, Svobodova Z.
Journal Article 2008; 29(5): 669-674 PubMed PMID: 18987601 Citation  Keywords:  Animals, Blood Cell Count, Carps:physiology, Cytochrome P-450 CYP1A1:metabolism, Cytochrome P-450 Enzyme System:metabolism, Erythrocyte Count, Herbicides:toxicity, Liver:drug effects, Triazines:toxicity, Vitellogenesis:drug effects, Water Pollutants, Chem.

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Evaluation of genotoxic and cytotoxic effects of H2O2 and DMNQ on freshly isolated rat hepatocytes; protective effects of carboxymethyl chitin-glucan.

Horvathova E, Eckl P, Bresgen N, Slamenova D.
Journal Article 2008; 29(5): 644-648 PubMed PMID: 18987600 Citation  Keywords:  Animals, Antioxidants, Apoptosis:drug effects, Cell Count, Cell Death, Cell Separation, Chitin:analogs & derivatives, Comet Assay, DNA:drug effects, DNA Damage:drug effects, Female, Glucans:pharmacology, Hepatocytes:drug effects, Hydrogen Peroxide:toxicit.

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Glucomannan in prevention of oxidative stress and inflammation occurring in adjuvant arthritis.

Bauerova K, Ponist S, Navarova J, Dubnickova M, Paulovicova E, Pajtinka M, Kogan G, Mihalova D.
Journal Article 2008; 29(5): 691-696 PubMed PMID: 18987599 Citation  Keywords:  Animals, Anti-Inflammatory Agents, Non-Steroidal, Antioxidants:metabolism, Arthritis, Experimental:pathology, Candida:chemistry, Foot:pathology, Inflammation:pathology, Male, Mannans:pharmacology, Mycobacterium:immunology, Oxidative Stress:drug effects, P.

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Human cytochromes P450 1A1 and 1A2 participate in detoxication of carcinogenic aristolochic acid.

Sistkova J, Hudecek J, Hodek P, Frei E, Schmeiser H, Stiborova M.
Journal Article 2008; 29(5): 733-737 PubMed PMID: 18987598 Citation  Keywords:  Animals, Aristolochic Acids:pharmacokinetics, Carcinogens:pharmacokinetics, Chromatography, High Pressure Liquid, Cytochrome P-450 CYP1A1:isolation & purification, Cytochrome P-450 CYP1A2:isolation & purification, Humans, Inactivation, Metabolic, Mice, Mi.

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Induction of cytochromes P450 in small intestine by chemopreventive compounds.

Krizkova J, Burdova K, Hudecek J, Stiborova M, Hodek P.
Journal Article 2008; 29(5): 717-721 PubMed PMID: 18987596 Citation  Keywords:  Allyl Compounds:pharmacology, Animals, Anticarcinogenic Agents:pharmacology, Blotting, Western, Curcumin:pharmacology, Cytochrome P-450 CYP1A1:biosynthesis, Cytochrome P-450 CYP2B1:biosynthesis, Cytochrome P-450 Enzyme System:biosynthesis, Flavonoids:phar.

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Inhibition of superoxide generation and myeloperoxidase release by carvedilol after receptor and nonreceptor stimulation of human neutrophils.

Macickova T, Pecivova J, Nosal R, Lojek A, Pekarova M, Cupanikova D.
Journal Article 2008; 29(5): 790-793 PubMed PMID: 18987595 Citation  Keywords:  Adrenergic beta-Antagonists:pharmacology, Androstadienes:pharmacology, Calcimycin:pharmacology, Carbazoles:pharmacology, Humans, In Vitro Techniques, Male, N-Formylmethionine Leucyl-Phenylalanine:pharmacology, Neutrophils:drug effects, Oxidants:metabolism.

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Interspecies comparison of the glucuronidation processes in the man, monkey, pig, dog and rat.

Matal J, Jancova P, Siller M, Masek V, Anzenbacherova E, Anzenbacher P.
Comparative Study 2008; 29(5): 738-743 PubMed PMID: 18987594 Citation  Keywords:  Animals, Dogs, Glucuronides:metabolism, Glucuronosyltransferase:metabolism, Haplorhini, Humans, Kinetics, Microsomes, Liver:enzymology, Protective Agents:metabolism, Rats, Silymarin:metabolism, Species Specificity, Swine,.

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Isolation and identification of the Amanita muscaria and Amanita pantherina toxins in human urine.

Merova B, Ondra P, Stankova M, Valka I.
Journal Article 2008; 29(5): 744-748 PubMed PMID: 18987593 Citation  Keywords:  Amanita:chemistry, Amanitins:urine, Chromatography, High Pressure Liquid, Humans, Ibotenic Acid:urine, Indicators and Reagents, Muscarine:urine, Muscimol:urine, Nucleic Acid Synthesis Inhibitors:urine, Solid Phase Extraction, Solvents, Spectrometry, Mass,.

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Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA.

Moserova M, Kotrbova V, Rupertova M, Naiman K, Hudecek J, Hodek P, Frei E, Stiborova M.
Journal Article 2008; 29(5): 728-732 PubMed PMID: 18987592 Citation  Keywords:  Acetyl Coenzyme A:metabolism, Arylamine N-Acetyltransferase:metabolism, Arylsulfotransferase:metabolism, Autoradiography, Catalysis, DNA:chemistry, DNA Adducts:chemistry, Deoxyguanosine:chemistry, Ellipticines:chemistry, Hydrogen-Ion Concentration, Indica.

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New performance of biosensor technology for Alzheimer's disease drugs: in vitro comparison of tacrine and 7-methoxytacrine.

Pohanka M, Kuca K, Kassa J.
Comparative Study 2008; 29(5): 755-758 PubMed PMID: 18987590 Citation  Keywords:  Acetylcholinesterase:chemistry, Algorithms, Alzheimer Disease:drug therapy, Biosensing Techniques, Cholinesterase Inhibitors:analysis, Electrochemistry, Enzymes, Immobilized:chemistry, Humans, Kinetics, Nootropic Agents:analysis, Tacrine:analogs & derivat.

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Oxidative impairment of plasma and skeletal muscle sarcoplasmic reticulum in rats with adjuvant arthritis - effects of pyridoindole antioxidants.

Strosova M, Tomaskova I, Ponist S, Bauerova K, Karlovska J, Spickett C, Horakova L.
Journal Article 2008; 29(5): 706-711 PubMed PMID: 18987589 Citation  Keywords:  Animals, Antioxidants:therapeutic use, Arthritis, Experimental:blood, Chromatography, High Pressure Liquid, Enzyme-Linked Immunosorbent Assay, Indoles:therapeutic use, Lipid Peroxidation:drug effects, Male, Mass Spectrometry, Muscle, Skeletal:drug effects.

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Potential antioxidant activity, cytotoxic and apoptosis-inducing effects of Chelidonium majus L. extract on leukemia cells.

Nadova S, Miadokova E, Alfoldiova L, Kopaskova M, Hasplova K, Hudecova A, Vaculcikova D, Gregan F, Cipak L.
Journal Article 2008; 29(5): 649-652 PubMed PMID: 18987588 Citation  Keywords:  Animals, Antineoplastic Agents, Phytogenic:pharmacology, Antioxidants:pharmacology, Apoptosis:drug effects, Biphenyl Compounds, Chelidonium:chemistry, Dose-Response Relationship, Drug, Free Radical Scavengers, HL-60 Cells, Humans, Leukemia:drug therapy, L.

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Prenatal developmental toxicity study of the pyridoindole antioxidant SMe1EC2 in rats.

Ujhazy E, Dubovicky M, Ponechalova V, Navarova J, Brucknerova I, Snirc V, Mach M.
Journal Article 2008; 29(5): 639-643 PubMed PMID: 18987587 Citation  Keywords:  Abnormalities, Drug-Induced:pathology, Animals, Antioxidants:toxicity, Female, Fetal Development:drug effects, Fetal Diseases:chemically induced, Indoles:toxicity, Neuroprotective Agents:toxicity, Pregnancy, Pyridines:toxicity, Rats, Rats, Wistar, Reprodu.

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Reversible asphyxial status in a newborn due to neonatal form of carnitine palmitoyltransferase II deficiency.

Brucknerova I, Bzduch V, Behulova D, Ferianec V, Dubovicky M, Ujhazy E, Mach M.
Case Reports 2008; 29(5): 627-630 PubMed PMID: 18987586 Citation  Keywords:  Asphyxia Neonatorum:enzymology, Cardiopulmonary Resuscitation, Carnitine O-Palmitoyltransferase:deficiency, Heart Failure:etiology, Humans, Infant, Newborn, Male, Respiratory Insufficiency:etiology, Tandem Mass Spectrometry,.

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Melatonin reduces oxidative/nitrosative stress due to drugs, toxins, metals, and herbicides.

Reiter R, Korkmaz A, Paredes S, Manchester L, Tan D.
Journal Article 2008; 29(5): 609-613 PubMed PMID: 18987585 Citation  Keywords:  Animals, Antioxidants:pharmacology, Drug-Related Side Effects and Adverse Reactions, Herbicides:toxicity, Humans, Melatonin:pharmacology, Metals:toxicity, Neurotoxins:toxicity, Oxidative Stress:drug effects, Prescription Drugs:toxicity, Reactive Nitrogen .

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Screening and semiquantitative analysis of drugs and drugs of abuse in human serum samples using gas chromatography-mass spectrometry.

Maresova V, Chadt J, Novakova E.
Journal Article 2008; 29(5): 749-754 PubMed PMID: 18987582 Citation  Keywords:  Acetamides, Calibration, Fluoroacetates, Gas Chromatography-Mass Spectrometry, Humans, Pharmaceutical Preparations:blood, Reproducibility of Results, Solid Phase Extraction, Substance Abuse Detection:methods, Substance-Related Disorders:blood, Trifluoroac.

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Structural analysis of binding of a diamantoid substrate to cytochrome P450 2B4: possible role of Arg 133 in modulation of function and activity of this enzyme.

Sulc M, Hudecek J, Stiborova M, Hodek P.
Journal Article 2008; 29(5): 722-727 PubMed PMID: 18987581 Citation  Keywords:  Adamantane:analogs & derivatives, Amino Acid Sequence, Animals, Arginine:genetics, Aryl Hydrocarbon Hydroxylases:antagonists & inhibitors, Chromatography, High Pressure Liquid, Crystallography, X-Ray, Cytochrome P450 Family 2, Enzyme Inhibitors:pharmacolo.

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Structure-efficiency relationship in derivatives of stilbene. Comparison of resveratrol, pinosylvin and pterostilbene.

Perecko T, Jancinova V, Drabikova K, Nosal R, Harmatha J.
Journal Article 2008; 29(5): 802-805 PubMed PMID: 18987580 Citation  Keywords:  Adenosine Triphosphate:metabolism, Antioxidants:pharmacology, Cell Survival:drug effects, Dose-Response Relationship, Drug, Humans, Luminescence, Neutrophils:drug effects, Reactive Oxygen Species:metabolism, Stilbenes:pharmacology, Structure-Activity Rela.

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Study of pro- and anti-oxidative properties of D-penicillamine in a system comprising high-molar-mass hyaluronan, ascorbate, and cupric ions.

Valachova K, Hrabarova E, Gemeiner P, Soltes L.
Journal Article 2008; 29(5): 697-701 PubMed PMID: 18987579 Citation  Keywords:  Antioxidants:chemistry, Ascorbic Acid:chemistry, Carbohydrate Sequence, Copper:chemistry, Free Radicals:chemistry, Hyaluronic Acid:chemistry, Hydrogen Peroxide:chemistry, Hydroxyl Radical:chemistry, Kinetics, Molecular Weight, Oxidants:chemistry, Penicill.

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The effect of aldose reductase inhibition by JMC-2004 on hyperglycemia-induced endothelial dysfunction.

Papezikova I, Pekarova M, Chatzopoulou M, Nicolaou I, Demopoulos V, Kubala L, Lojek A.
Journal Article 2008; 29(5): 775-778 PubMed PMID: 18987578 Citation  Keywords:  Aldehyde Reductase:antagonists & inhibitors, Animals, Blotting, Western, Calcimycin:pharmacology, Cattle, Cell Line, Electrochemistry, Endothelial Cells:drug effects, Endothelium, Vascular:drug effects, Enzyme Inhibitors:pharmacology, Glucose:pharmacology.

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The effect of HI-6 on cholinesterases and on the cholinergic system of the rat bladder.

Soukup O, Pohanka M, Tobin G, Jun D, Fusek J, Musilek K, Marek J, Kassa J, Kuca K.
Journal Article 2008; 29(5): 759-762 PubMed PMID: 18987577 Citation  Keywords:  Acetylcholinesterase:metabolism, Animals, Biosensing Techniques, Butyrylcholinesterase:metabolism, Cholinesterase Inhibitors:pharmacology, Methacholine Chloride:pharmacology, Muscarinic Agonists:pharmacology, Oximes, Parasympathetic Nervous System:drug ef.

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The use of wireless capsule enteroscopy in a preclinical study: a novel diagnostic tool for indomethacin-induced gastrointestinal injury in experimental pigs.

Kvetina J, Kunes M, Bures J, Kopacova M, Tachecí I, Spelda S, Herout V, Rejchrt S.
Journal Article 2008; 29(5): 763-769 PubMed PMID: 18987574 Citation  Keywords:  Animals, Anti-Inflammatory Agents, Non-Steroidal:toxicity, Capsule Endoscopy:methods, Female, Gastric Mucosa:pathology, Gastroscopy, Indomethacin:toxicity, Intestinal Mucosa:pathology, Microscopy, Confocal, Peptic Ulcer:chemically induced, Swine,.

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