Vol. 29 (5) 2008 Neuro endocrinology letters

Effect of transient ischemia on long-term potentiation of synaptic transmission in rat hippocampal slices.

OBJECTIVES: Long-term potentiation (LTP) of neuronal activity in the hippocampus is thought to be a substrate for learning and memory. The influence of ischemia (IS) (hypoxia/hypoglycemia) on induction of LTP of synaptic transmission (ST) by high frequency stimulation (HFS) was investigated in rat hippocampal slices.

METH.....