Vol. 29 (5) 2008 Neuro endocrinology letters

Hyaluronan influence on the onset of chondrogenic differentiation of mesenchymal stem cells.

OBJECTIVES: Hyaluronan (HA) is an abundant component of chondrogenic tissue hence it is often used as a fundamental constituent in cartilage tissue substitutes. However, effects of different molecular weight HA on chondrogenic differentiation are not clear. The aim was to evaluate modulation of mesenchymal stem cell (MSC) early chondrog.....