Vol. 33 (Suppl 3) 2012 Neuro endocrinology letters

Tacrine is implicated in oxidative stress in the laboratory guinea pig model.

Kracmarova A, Bandouchova H, Pikula J, Pohanka M.

Journal Article 2012; 33(Suppl 3): 136-144 PubMed PMID: 23353857 Citation  Keywords:  Alzheimer Disease:chemically induced, Animals, Antioxidants:metabolism, Brain:drug effects, Caspase 3:metabolism, Chemical and Drug Induced Liver Injury:metabolism, Cholinesterase Inhibitors:toxicity, Disease Models, Animal, Female, Guinea Pigs, Heart:dru.

OBJECTIVES: Tacrine was the first acetylcholinesterase inhibitor approved for the treatment of Alzheimer disease. The compound is not available for therapeutic purposes as it was withdrawn due to hepatotoxicity of its metabolites. The hepatotoxicity can be decreased by alternative ways of drug administration avoiding thus the first pass.....

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Effects of novel quercetin derivatives on sarco/endoplasmic reticulum Ca2+-ATPase activity.

Blaskovic D, Drzik F, Viskupicova J, Zizkova P, Veverka M, Horakova L.
Journal Article 2012; 33(Suppl 3): 190-197 PubMed PMID: 23353866 Citation  Keywords:  Animals, Antioxidants:metabolism, Drug Interactions, Endoplasmic Reticulum:drug effects, Enzyme Activation:drug effects, Female, Muscle, Skeletal:drug effects, Peroxynitrous Acid:biosynthesis, Quercetin:analogs & derivatives, Rabbits, Sarcoplasmic Reticul.

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Melatonin influences antioxidant homeostasis and basal metabolism in the BALB/c mouse model.

Pohanka M, Bandouchova H, Pikula J.
Journal Article 2012; 33(Suppl 3): 183-189 PubMed PMID: 23353865 Citation  Keywords:  Animals, Antioxidants:metabolism, Basal Metabolism:drug effects, Biomarkers:metabolism, Caspases:metabolism, Female, Homeostasis:drug effects, Melatonin:metabolism, Mice, Mice, Inbred BALB C, Models, Animal, Oxidative Stress:drug effects, Thiobarbituric A.

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Stimulation of nitric oxide, cytokine and prostaglandin production by low-molecular weight fractions of probiotic Lactobacillus casei lysate.

Kmonickova E, Kverka M, Tlaskalová-Hogenová H, Kostecka P, Zidek Z.
Journal Article 2012; 33(Suppl 3): 166-172 PubMed PMID: 23353862 Citation  Keywords:  Animals, Bacterial Proteins:chemistry, Cells, Cultured, Chemical Fractionation, Cytokines:biosynthesis, Dinoprostone:biosynthesis, Female, Lactobacillus casei:metabolism, Lipopolysaccharides:chemistry, Molecular Weight, Nitric Oxide:biosynthesis, Peptidog.

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Avian high-dose toxicity of cyanobacterial biomass.

Kral J, Pikula J, Bandouchova H, Damkova V, Hilscherova K, Misik J, Novotny L, Ondracek K, Osickova J, Mlcakova V, Pohanka M, Skochova H, Vitula F, Treml F.
Journal Article 2012; 33(Suppl 3): 161-165 PubMed PMID: 23353861 Citation  Keywords:  Animals, Bacterial Toxins:toxicity, Biomass, Body Weight, Carcinogens:toxicity, Chemical and Drug Induced Liver Injury:epidemiology, Coturnix, Cyanobacteria:chemistry, Dose-Response Relationship, Drug, Hepatocytes:drug effects, Lethal Dose 50, Male, Marin.

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Risk of combined exposure of birds to cyanobacterial biomass containing microcystins, acetylcholinesterase inhibitor and anticoagulant.

Ondracek K, Bandouchova H, Damkova V, Hilscherova K, Kral J, Osickova J, Mlcakova V, Pohanka M, Skochova H, Vitula F, Treml F, Pikula J.
Journal Article 2012; 33(Suppl 3): 155-160 PubMed PMID: 23353860 Citation  Keywords:  4-Hydroxycoumarins:toxicity, Animals, Anticoagulants:toxicity, Biomass, Brain:drug effects, Carcinogens:toxicity, Cholinesterase Inhibitors:toxicity, Coturnix, Cyanobacteria:chemistry, Female, Heart:drug effects, Kidney:drug effects, Liver:drug effects, L.

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Free-radical degradation of high-molar-mass hyaluronan induced by Weissberger's oxidative system: potential antioxidative effect of bucillamine.

Banasova M, Sasinkova V, Mendichi R, Perecko T, Valachova K, Juranek I, Soltes L.
Journal Article 2012; 33(Suppl 3): 151-154 PubMed PMID: 23353859 Citation  Keywords:  Antioxidants:chemistry, Ascorbic Acid:chemistry, Copper:chemistry, Cysteine:analogs & derivatives, Extracellular Matrix:chemistry, Free Radicals:chemistry, Humans, Hyaluronic Acid:chemistry, Molecular Weight, Oxidation-Reduction, Spectroscopy, Fourier Tra.

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Risk of single and combined exposure of birds to non-steroidal anti-inflammatory drugs and lead.

Osickova J, Skochova H, Ondracek K, Kral J, Damkova V, Peckova L, Pohanka M, Vitula F, Bandouchova H, Pikula J.
Journal Article 2012; 33(Suppl 3): 145-150 PubMed PMID: 23353858 Citation  Keywords:  Animals, Anti-Inflammatory Agents, Non-Steroidal:toxicity, Blood Proteins:metabolism, Coturnix, Diclofenac:toxicity, Drug Synergism, Environmental Pollutants:toxicity, Gastrointestinal Tract:drug effects, Hemoglobins:metabolism, Lead:toxicity, Lead Poison.

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Effect of chronic exposure to prometryne on oxidative stress and antioxidant response in early life stages of common carp (Cyprinus carpio L.).

Stara A, Machova J, Velisek J.
Journal Article 2012; 33(Suppl 3): 130-135 PubMed PMID: 23353856 Citation  Keywords:  Animals, Antioxidants:metabolism, Biomarkers:metabolism, Carps:embryology, Catalase:metabolism, Czech Republic, Embryo, Nonmammalian:drug effects, Female, Glutathione Reductase:metabolism, Herbicides:toxicity, Male, Oxidative Stress:drug effects, Prometry.

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Oxidative stress parameters in early developmental stages of common carp (Cyprinus carpio L.) after subchronic exposure to terbuthylazine and metribuzin.

Hostovsky M, Blahova J, Plhalova L, Stepanova S, Praskova E, Marsalek P, Svobodova Z.
Journal Article 2012; 33(Suppl 3): 124-129 PubMed PMID: 23353855 Citation  Keywords:  Animals, Biomarkers:metabolism, Carps:embryology, Dose-Response Relationship, Drug, Embryo, Nonmammalian:drug effects, Free Radicals:metabolism, Herbicides:toxicity, Lipid Peroxidation:drug effects, Oxidative Stress:drug effects, Phenols:metabolism, Plant.

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Influence of cyanobacteria on water activity and dry matter of muscles in the common carp (Cyprinus carpio L.) and rainbow trout (Oncorhynchus mykiss W.).

Navratil L, Vlasek V, Langova J, Palikova M, Brabec T, Mares J, Kopp R, Klima Z, Navratil S.
Journal Article 2012; 33(Suppl 3): 120-123 PubMed PMID: 23353854 Citation  Keywords:  Animal Feed, Animals, Aquaculture:methods, Bacterial Toxins:toxicity, Carps:growth & development, Cryopreservation, Cyanobacteria, Ecosystem, Marine Toxins:toxicity, Microcystins:toxicity, Muscle, Skeletal:anatomy & histology, Oncorhynchus mykiss:growth &.

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The effects of subchronic exposure to terbuthylazine on zebrafish.

Plhalova L, Stepanova S, Blahova J, Praskova E, Hostovsky M, Skoric M, Zelnickova L, Svobodova Z, Bedanova I.
Journal Article 2012; 33(Suppl 3): 113-119 PubMed PMID: 23353853 Citation  Keywords:  Animals, Chemical and Drug Induced Liver Injury:metabolism, Dose-Response Relationship, Drug, Gills:drug effects, Hepatocytes:drug effects, Herbicides:pharmacokinetics, Kidney:drug effects, Models, Biological, Thiobarbituric Acid Reactive Substances:metab.

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Effect of β-1.3/1.6-D-glucan derived from oyster mushroom Pleurotus ostreatus on biometrical, haematological, biochemical, and immunological indices in rainbow trout (Oncorhynchus mykiss).

Dobsikova R, Blahova J, Franc A, Jakubik J, Mikulikova I, Modra H, Novotna K, Svobodova Z.
Journal Article 2012; 33(Suppl 3): 96-106 PubMed PMID: 23353851 Citation  Keywords:  Adjuvants, Immunologic:pharmacology, Animal Feed, Animals, Blood Proteins:metabolism, Dose-Response Relationship, Drug, Fisheries:methods, Immune System:drug effects, Oncorhynchus mykiss:blood, Pleurotus:chemistry, beta-Glucans:pharmacology,.

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Effects of low-concentrations of simazine on early life stages of common carp (Cyprinus carpio L.).

Velisek J, Stara A, Machova J, Dvorak P, Zuskova E, Svobodova Z.
Journal Article 2012; 33(Suppl 3): 90-95 PubMed PMID: 23353850 Citation  Keywords:  Animals, Carps:embryology, Czech Republic, Dose-Response Relationship, Drug, Embryo, Nonmammalian:drug effects, Female, Herbicides:toxicity, Kidney:drug effects, Male, Models, Biological, Ovum:drug effects, Rivers:chemistry, Simazine:toxicity, Toxicity Te.

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Content of selected metals in muscle of cyprinid fish species from the Nitra River, Slovakia.

Andreji J, Dvorak P, Dvorakova Liskova Z, Massányi P, Stranai I, Nad P, Skalicka M.
Journal Article 2012; 33(Suppl 3): 84-89 PubMed PMID: 23353849 Citation  Keywords:  Animals, Cadmium:metabolism, Copper:metabolism, Cyprinidae:metabolism, Environmental Monitoring, Food Contamination, Humans, Iron:metabolism, Lead:metabolism, Manganese:metabolism, Metals:metabolism, Muscle, Skeletal:metabolism, Nickel:metabolism, Rivers:.

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Combined exposure of carps (Cyprinus carpio L.) to cyanobacterial biomass and white spot disease.

Palikova M, Navratil S, Papezikova I, Ambroz P, Vesely T, Pokorova D, Mares J, Adamovsky O, Navratil L, Kopp R.
Journal Article 2012; 33(Suppl 3): 77-83 PubMed PMID: 23353848 Citation  Keywords:  Animals, Bacterial Toxins:toxicity, Biomass, Carcinogens:toxicity, Carps:immunology, Ciliophora, Cyanobacteria:growth & development, Fish Diseases:immunology, Immune System:immunology, Leukocyte Count, Marine Toxins:toxicity, Microcystins:toxicity, Protoz.

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Acute toxicity of acetylsalicylic acid to juvenile and embryonic stages of Danio rerio.

Praskova E, Zivna D, Stepanova S, Sevcikova M, Blahova J, Marsalek P, Siroka Z, Voslarova E, Svobodova Z.
Journal Article 2012; 33(Suppl 3): 72-76 PubMed PMID: 23353847 Citation  Keywords:  Animals, Anti-Inflammatory Agents, Non-Steroidal:toxicity, Aspirin:toxicity, Dose-Response Relationship, Drug, Embryo, Nonmammalian:drug effects, Inactivation, Metabolic:physiology, Lethal Dose 50, Oxidative Stress:drug effects, Toxicity Tests, Acute, Wat.

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Comparison of the effects of four anaesthetics on haematological and blood biochemical profiles in pikeperch (Sander lucioperca L.).

Kristan J, Stara A, Turek J, Policar T, Velisek J.
Comparative Study 2012; 33(Suppl 3): 66-71 PubMed PMID: 23353846 Citation  Keywords:  Aminobenzoates:toxicity, Anesthetics:pharmacology, Animals, Aquaculture:methods, Blood Proteins:metabolism, Clove Oil:pharmacology, Erythrocyte Count, Esocidae:blood, Ethylene Glycols:pharmacology, Etomidate:pharmacology, Hematocrit, Perches:blood,.

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Effect of four selected carrier solvents on embryonal stages of Danio rerio.

Chromcova L, Stepanova S, Plhalova L, Praskova E, Svobodova Z.
Comparative Study 2012; 33(Suppl 3): 60-65 PubMed PMID: 23353845 Citation  Keywords:  Abnormalities, Multiple:chemically induced, Acetone:toxicity, Animals, Dimethyl Sulfoxide:toxicity, Dose-Response Relationship, Drug, Edema:chemically induced, Embryo, Nonmammalian:drug effects, Ethanol:toxicity, Eye Abnormalities:chemically induced, Meth.

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Toxicity hazard of organophosphate insecticide malathion identified by in vitro methods.

Jira D, Janousek S, Pikula J, Vitula F, Kejlova K.
Journal Article 2012; 33(Suppl 3): 53-59 PubMed PMID: 23353844 Citation  Keywords:  Animals, BALB 3T3 Cells:cytology, Chick Embryo, Chickens, Chorioallantoic Membrane:cytology, Cornea:cytology, Dose-Response Relationship, Drug, Embryo, Nonmammalian:cytology, In Vitro Techniques, Insecticides:toxicity, Irritants:toxicity, Linear Models, M.

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The influence of rosuvastatin on liver microsomal CYP2C6 in hereditary hypertriglyceridemic rat.

Vecera R, Zacharová A, Siller M, Matuskova Z, Skottová N, Anzenbacherová E, Anzenbacher P.
Journal Article 2012; 33(Suppl 3): 48-52 PubMed PMID: 23353843 Citation  Keywords:  Animals, Aryl Hydrocarbon Hydroxylases:antagonists & inhibitors, Cholesterol, Dietary:pharmacology, Cytochrome P-450 CYP2C9, Cytochrome P450 Family 2, Fluorobenzenes:pharmacology, Gene Expression Regulation, Enzymologic:drug effects, Humans, Hydroxymethyl.

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Mapping of interaction between cytochrome P450 2B4 and cytochrome b5: the first evidence of two mutual orientations.

Sulc M, Jecmen T, Snajdrova R, Novak P, Martinek V, Hodek P, Stiborova M, Hudecek J.
Journal Article 2012; 33(Suppl 3): 41-47 PubMed PMID: 23353842 Citation  Keywords:  Animals, Aryl Hydrocarbon Hydroxylases:chemistry, Carbodiimides:chemistry, Chromatography, Liquid:methods, Cross-Linking Reagents:chemistry, Cytochrome P450 Family 2, Cytochromes b5:chemistry, Dimerization, Electrons, Mass Spectrometry:methods, Microsomes.

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Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1.

Jerabek P, Martinek V, Stiborova M.
Journal Article 2012; 33(Suppl 3): 25-32 PubMed PMID: 23353840 Citation  Keywords:  Amino Acid Sequence, Aristolochia:chemistry, Aristolochic Acids:adverse effects, Aryl Hydrocarbon Hydroxylases:chemistry, Catalytic Domain:drug effects, Computer Simulation, Cytochrome P-450 CYP1A1:chemistry, Cytochrome P-450 CYP1A2:chemistry, Cytochrome .

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Impact of histone deacetylase inhibitor valproic acid on the anticancer effect of etoposide on neuroblastoma cells.

Groh T, Hrabeta J, Poljakova J, Eckschlager T, Stiborova M.
Journal Article 2012; 33(Suppl 3): 16-24 PubMed PMID: 23353839 Citation  Keywords:  Antineoplastic Agents, Phytogenic:pharmacology, Apoptosis:drug effects, Bone Marrow Neoplasms:drug therapy, Brain Neoplasms:drug therapy, Cell Cycle:drug effects, Cell Line, Tumor, Drug Resistance, Neoplasm:drug effects, Drug Synergism, Etoposide:pharmaco.

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Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes.

Stiborova M, Cechova T, Borek-Dohalska L, Moserova M, Frei E, Schmeiser H, Paca J, Arlt V.
Journal Article 2012; 33(Suppl 3): 8-15 PubMed PMID: 23353838 Citation  Keywords:  Aerobiosis:physiology, Air Pollutants:pharmacokinetics, Anaerobiosis:physiology, Animals, Benz(a)Anthracenes:pharmacokinetics, Carcinogens:pharmacokinetics, Cytochrome P-450 Enzyme System:metabolism, Cytochrome-B(5) Reductase:genetics, DNA Adducts:metabol.

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