The insulin receptor substrate-4 (IRS-4) gene and schizophrenia: no evidence for a main genetic factor, however one report of a single schizophrenia patient with a mutation.

Melkersson K, Persson B, Hongslo T.

Journal Article 2011; 32(1): 52-58 PubMed PMID: 21407155 Keywords: Adult, Case-Control Studies, Female, Genetic Predisposition to Disease, Haplotypes, Humans, Insulin Receptor Substrate Proteins:genetics, Male, Middle Aged, Point Mutation, Polymorphism, Single Nucleotide, Schizophrenia:genetics,.

OBJECTIVES: Since there are clear indications that schizophrenia is a systemic disorder, we sought for a common molecular basis for schizophrenia abnormalities in brain and body. Our hypothesis was that an impaired insulin/ insulin-like growth factor signalling in cells might underlie both structural and functional brain changes and per.....

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Vol. 32 (1) 2011 Neuro endocrinology letters

The insulin receptor substrate-4 (IRS-4) gene and schizophrenia: no evidence for a main genetic factor, however one report of a single schizophrenia patient with a mutation.

Depression's multiple comorbidities explained by (neuro)inflammatory and oxidative & nitrosative stress pathways.

Aerobic exercise has beneficial impact on atherogenic index of plasma in sedentary overweigh and obese women.

Correction of steroidopenia as a new method of hypercholesterolemia treatment.

Delayed effect of chronic administration of corticoids on the taste aversion learning.

Differential effects of stable elevated levels of corticotropin-releasing hormone and systemic corticosterone on various types of rat learning.

Drug-induced systemic lupus erythematosus in interferon beta-1b therapy.

Expression of somatostatin receptor subtypes in primary and recurrent gonadotropinomas: are somatostatin receptors involved in pituitary adenoma recurrence?

Increased plasma arginine vasopressin levels in dopamine agonist-treated Parkinson's disease patients.

Is the PIK3CA gene expression level in FNAB washouts equivalent to that in postoperative tissue specimens of papillary thyroid carcinoma?

Placenta - organ important for fetus and interesting for the rise of the Attention Deficit Hyperactivity Disorder Syndrome - interdisciplinary study.

Pregnancy and periodontal tissues.

The influence of cocaine-amphetamine regulated transcript (CART) on pituitary hormones, corticosterone and leptin levels in starved rats.

The role of selected immunoregulatory cell populations in autoimmune demyelination.

Tubo-ovarian abscess during therapy of chronic hepatitis C with pegylated interferon and ribavirin.