Vol. 26 (6) 2005 Neuro endocrinology letters

Reproductive toxic effects of Topamax ingestion in female Sprague-Dawley rats.

PURPOSE: The objectives of this study is to investigate the toxic effects of Topamax (100 mg/kg/body weight) on the reproductive system after administration to female Sprague-Dawley rats weighing 250-300 g for two time periods 4 and 12 weeks.

METHODS: Twenty adult female rats were divided into two groups and expo.....