Vol. 26 (4) 2005 Neuro endocrinology letters

Ibuprofen reduces plasma nitrite/nitrate levels in a rabbit model of endotoxin-induced shock.

OBJECTIVES: The purpose of this study was to investigate the effects of ibuprofen on plasma nitrite/nitrate levels, as indirect indicators of nitric oxide, in correlation with blood pressure in a rabbit model of endotoxin-induced shock.

METHODS: A total of 28 rabbits were randomly divided into four groups. Contro.....