Vol. 23 (4) 2002 Neuro endocrinology letters

The effects of interleukin-6, leukemia inhibitory factor and interferon-gamma on STAT DNA binding and c-fos mRNA levels in cortical astrocytes and C6 glioma cells.

OBJECTIVES: The purpose of this study was to compare the effects of neurotrophic cytokines on the JAK/STAT transcription factors and the immediate early gene, c-fos, in C6 glioma cells and in primary astrocyte cultures.

METHODS: In this study we compared the effects of interleukin 6, leukemia inhibitory factor an.....