Articles by author - Simon Scharpe

Faulty serotonin--DHEA interactions in autism: results of the 5-hydroxytryptophan challenge test.

Croonenberghs J, Spaas K, Wauters A, Verkerk R, Scharpe S, Deboutte D, Maes M.

Journal Article 2008; 29(3): 385-390 PubMed PMID: 18580847  Keywords:  5-Hydroxytryptophan, Adolescent, Analysis of Variance, Autistic Disorder:blood, Dehydroepiandrosterone Sulfate:blood, Humans, Hydrocortisone:blood, Male, Psychiatric Status Rating Scales, Serotonin:blood, Single-Blind Method,.    Citation

BACKGROUND: Autism is accompanied by peripheral and central disorders in the metabolism of serotonin (5-HT). The present study examines pl.....

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Central serotonergic hypofunction in autism: results of the 5-hydroxy-tryptophan challenge test.

Croonenberghs J, Wauters A, Deboutte D, Verkerk R, Scharpe S, Maes M.

Journal Article 2007; 28(4): 449-455 PubMed PMID: 17693983  Keywords:  5-Hydroxytryptophan:administration & dosage, Adolescent, Adult, Analysis of Variance, Antidepressive Agents, Second-Generation:administration & dosage, Autistic Disorder:blood, Case-Control Studies, Child, Humans, Hydrocortisone:blood, Male, Prolactin:blo.    Citation

: Some studies have suggested that disorders in the central serotonergic function may play a role in the pathophysiology of autistic disor.....

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