Papezikova I, Pekarova M, Lojek A, Kubala L.
Journal Article 2009; 30(Suppl 1): 112-115 PubMed PMID: 20027155 Keywords: Animals, Aorta, Blotting, Western, Calcimycin:pharmacology, Cattle, Cells, Cultured, Endothelial Cells:drug effects, Homocysteine:metabolism, Ionophores:pharmacology, Kinetics, Microelectrodes, Nitric Oxide:metabolism, Nitric Oxide Synthase Type III:metab. CitationOBJECTIVES: Elevated plasma uric acid indicates an increased risk of cardiovascular diseases associated with endothelial dysfunction. Howe.....
Papezikova I, Pekarova M, Lojek A, Kubala L. The effect of uric acid on homocysteine-induced endothelial dysfunction in bovine aortic endothelial cells. Neuro Endocrinol Lett. 2009 Jan; 30(Suppl 1): 112-115
Konopka R, Kubala L, Lojek A, Pacherník J.
Journal Article 2008; 29(5): 770-774 PubMed PMID: 18987612 Keywords: Acetophenones:pharmacology, Acetylcysteine:pharmacology, Ascorbic Acid:pharmacology, Blotting, Western, Cell Differentiation:drug effects, Embryonal Carcinoma Stem Cells:drug effects, Flow Cytometry, Free Radical Scavengers:pharmacology, Genes, Reporter:d. CitationOBJECTIVES: Intracellularly generated reactive oxygen species (ROS) are thought to modulate redox sensitive signaling pathways and thus re.....
Konopka R, Kubala L, Lojek A, Pacherník J. Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production. Neuro Endocrinol Lett. 2008 Oct; 29(5): 770-774
Lojek A, Pecivova J, Macickova T, Nosal R, Papezikova I, Ciz M.
Journal Article 2008; 29(5): 779-783 PubMed PMID: 18987604 Keywords: Adenosine Triphosphate:metabolism, Adrenergic beta-Antagonists:pharmacology, Carbazoles:pharmacology, Cell Differentiation:drug effects, Cell Proliferation:drug effects, Fluorometry, Granulocytes:drug effects, HL-60 Cells, Humans, Luminescence, Nitric Oxi. CitationOBJECTIVES: The generation of reactive oxygen species (ROS) by phagocytes is one of the irreplaceable microbicidal tools of innate immunit.....
Lojek A, Pecivova J, Macickova T, Nosal R, Papezikova I, Ciz M. Effect of carvedilol on the production of reactive oxygen species by HL-60 cells. Neuro Endocrinol Lett. 2008 Oct; 29(5): 779-783
Macickova T, Pecivova J, Nosal R, Lojek A, Pekarova M, Cupanikova D.
Journal Article 2008; 29(5): 790-793 PubMed PMID: 18987595 Keywords: Adrenergic beta-Antagonists:pharmacology, Androstadienes:pharmacology, Calcimycin:pharmacology, Carbazoles:pharmacology, Humans, In Vitro Techniques, Male, N-Formylmethionine Leucyl-Phenylalanine:pharmacology, Neutrophils:drug effects, Oxidants:metabolism. CitationOBJECTIVES: To compare three stimuli which activate human neutrophils with different signal transduction mechanisms, in order to better lo.....
Macickova T, Pecivova J, Nosal R, Lojek A, Pekarova M, Cupanikova D. Inhibition of superoxide generation and myeloperoxidase release by carvedilol after receptor and nonreceptor stimulation of human neutrophils. Neuro Endocrinol Lett. 2008 Oct; 29(5): 790-793
Papezikova I, Pekarova M, Chatzopoulou M, Nicolaou I, Demopoulos V, Kubala L, Lojek A.
Journal Article 2008; 29(5): 775-778 PubMed PMID: 18987578 Keywords: Aldehyde Reductase:antagonists & inhibitors, Animals, Blotting, Western, Calcimycin:pharmacology, Cattle, Cell Line, Electrochemistry, Endothelial Cells:drug effects, Endothelium, Vascular:drug effects, Enzyme Inhibitors:pharmacology, Glucose:pharmacology. CitationOBJECTIVES: An increased glucose utilization by aldose reductase (ALR-2) has been implicated in the pathogenesis of diabetic vascular comp.....
Papezikova I, Pekarova M, Chatzopoulou M, Nicolaou I, Demopoulos V, Kubala L, Lojek A. The effect of aldose reductase inhibition by JMC-2004 on hyperglycemia-induced endothelial dysfunction. Neuro Endocrinol Lett. 2008 Oct; 29(5): 775-778
Pecivová J, Macicková T, Lojek A, Gallová L, Cíz M, Nosál' R, Holománová D.
Journal Article 2006; 27(Suppl 2): 160-163 PubMed PMID: 17159805 Keywords: Animals, Carbazoles:pharmacology, Cells, Cultured, Immunity, Cellular:drug effects, Immunity, Innate:drug effects, Macrophages:drug effects, Mice, N-Formylmethionine Leucyl-Phenylalanine:pharmacology, Nitric Oxide Synthase Type II:metabolism, Peroxidase:m. CitationOBJECTIVES: Neutrophils and macrophages are critical components of our innate host defenses. They are a potential source of nitric oxide (.....
Pecivová J, Macicková T, Lojek A, Gallová L, Cíz M, Nosál' R, Holománová D. Effect of carvedilol on reactive oxygen species and enzymes linking innate and adaptive immunity. Neuro Endocrinol Lett. 2006 Dec; 27(Suppl 2): 160-163