Vol. 30 (Suppl 1) 2009 Neuro endocrinology letters

Influence of probiotics on rat liver biotransformation enzymes.

OBJECTIVES: The aim of the study was to find, whether probiotic Escherichia coli Nissle 1917 O6:K5:H1 (EcN) influence the amount and activity of cytochromes P450 (CYP) in rat liver.

DESIGN: Live bacterial suspension of EcN was applied to the female Wistar rats in single dose or for 14 days consecutively. The bact.....