Vol. 29 (6) 2008 Neuro endocrinology letters

Chronic isolation of adult rats decreases gene expression of catecholamine biosynthetic enzymes in adrenal medulla.

OBJECTIVE: Isolation of adult animals represents a form of psychsocial stress that produces sympatho-adrenomedullar activation. The aim of this work was to investigate the changes in gene expression and protein levels of catecholamine biosynthetic enzymes: tyrosine hydroxylase (TH), dopamine-beta-hydroxylase (DBH) and phenylethanolamine.....