Vol. 29 (6) 2008 Neuro endocrinology letters

Effect of Nogo-A gene inhibition on dopamine release in PC12 cells.

OBJECTIVES: Reticulon proteins, which are localized in the endoplasmic reticulum, have recently been shown to be involved in hormone secretion, in particular RTN1 and RTN3. The aim of the present study was to examine the effects of Nogo-A gene expression knockdown by RNA interference (RNAi) on dopamine release in PC12 cells.

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