Vol. 29 (6) 2008 Neuro endocrinology letters

Enhancement of neutral endopeptidase activity in SK-N-SH cells by ginsenoside Rb1.

OBJECTIVES: To investigate the effect of ginsenosides Rb1 and Rg1 on Neprilysin (NEP) activity in SK-N-SH cells, and probe the underlying mechanism.

METHODS: The effects of ginsenosides Rb1 and Rg1 on NEP activity were analyzed by NEP peptidase assay. Western blot was used to determine NEP gene expression at tran.....