Vol. 28 (3) 2007 Neuro endocrinology letters

Effect of melatonin on exploration and anxiety in normotensive and hypertensive rats with high activity of renin-angiotensin system.

OBJECTIVES: The purpose of the study was to investigate effects of melatonin (MEL) on exploration and anxiety in normotensive Sprague-Dawley (SD) and hypertensive TGR(mREN2)27 (TGR) rats with high activity of renin-angiotensin system.

METHODS: Mature control (n=20) and hypertensive (n=20) rats were used. Half of .....