Vol. 28 (3) 2007 Neuro endocrinology letters

Effects of long-term use of fluoxetine on fertility parameters in adult male rats.

: The effects of long-term ingestion of fluoxetine on fertility were investigated in Sprague-Dawley male rats. Adult male rats were exposed to fluoxetine at a concentration of 200 mg/kg for 60 days. Long-term ingestion of fluoxetine for 60 days caused a great decrease in spermatogenesis in seminiferous tubules of the testes. Sperm motil.....