Butyrate sensitizes the release of substance P and calcitonin gene-related peptide evoked by capsaicin from primary cultured rat dorsal root ganglion neurons.

Xing Y, Liu Z, Wang L, Huang F, Wang H, Li Z.

Journal Article 2006; 27(6): 695-701 PubMed PMID: 17187013 Keywords: Animals, Butyrates:pharmacology, Calcitonin Gene-Related Peptide:genetics, Capsaicin:pharmacology, Cells, Cultured, Dose-Response Relationship, Drug, Ganglia, Spinal:cytology, Irritants:pharmacology, Neurons:drug effects, Neurosecretion:drug effects, RNA,.

OBJECTIVES: To investigate whether butyrate increases substance P (SP) and calcitonin gene-related peptide (CGRP) release evoked by capsaicin from primary cultured dorsal root ganglion (DRG) neurons.

METHODS: DRG was dissected out from embryonic 15-day-old Wistar rat and cultured as dissociate cells for 24 h then.....

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Vol. 27 (6) 2006 Neuro endocrinology letters

Butyrate sensitizes the release of substance P and calcitonin gene-related peptide evoked by capsaicin from primary cultured rat dorsal root ganglion neurons.

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