Vol. 27 (6) 2006 Neuro endocrinology letters

Effects of testosterone on differentiation and oxidative stress resistance in C1300 neuroblastoma cells.

OBJECTIVES: Using undifferentiated mouse neuroblastoma cells (C1300), we have previously observed that testosterone (T) exerts a neuroprotective action against oxidative stress. Nitrogen intermediates induce the production of 3-nitro-L-tyrosine (3NT), an amino acid analogue involved in many neurodegenerative disorders. The aim of our wo.....