Vol. 33 (5) 2012 Neuro endocrinology letters

Ascorbic acid and alpha-tocopherol protect age-dependently from hypoxia-induced changes of cortical excitability in developing rats.

OBJECTIVES: The effects of ascorbic acid and α-tocopherol pre-treatment on hypoxia induced changes in brain cortex excitability were tested in immature rats exposed chronically to simulated altitude of 7 000 m.

METHODS: Rat pups were kept together with their mothers for 8 hours a day in hypobaric chamber since.....