Articles by author - Stanislav Smrcek

Oxidative detoxication of carcinogenic 2-nitroanisole by human, rat and rabbit cytochrome P450.

Dracínska H, Miksanová M, Svobodová M, Smrcek S, Frei E, Schmeiser H, Stiborová M.

Journal Article 2006; 27(Suppl 2): 9-13 PubMed PMID: 17159769  Keywords:  Adolescent, Adult, Aged, Aniline Compounds:metabolism, Animals, Anisoles:pharmacokinetics, Carcinogens:pharmacokinetics, Child, Child, Preschool, Cytochrome P-450 Enzyme System:metabolism, Female, Humans, In Vitro Techniques, Male, Metabolic Detoxication,.    Citation

OBJECTIVES: The detoxifying metabolism of a potent rodent carcinogen, 2-nitroanisole (2-NA) by human, rabbit and rat cytochromes P450 (P45.....

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