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Articles by author - Khalid Z Matalka

Pomegranate and licorice juices modulate metformin pharmacokinetics in rats.

Awad R, Mallah E, Khawaja B, Dayyih W, El-Hajji F, Matalka K, Arafat T.

Journal Article 2016; 37(3): 202-206 PubMed PMID: 27618606  Keywords:  Animals, Area Under Curve, Beverages, Chromatography, High Pressure Liquid, Female, Food-Drug Interactions, Glycyrrhiza, Hypoglycemic Agents:pharmacokinetics, Male, Metformin:pharmacokinetics, Punicaceae, Rats, Rats, Sprague-Dawley, Reproducibility of Res.    Citation

OBJECTIVES: Food or drinks may significantly alter the pharmacokinetics and pharmacodynamics of drugs which may lead to adverse events. A .....

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Dopamine selectively modulates lipopolysaccharide-induced TNF-alpha, IFN-gamma and IL-10 within mice tissues.

Matalka K, Attallah L, Qinna N, Alhussainy T.

Journal Article 2011; 32(2): 176-186 PubMed PMID: 21552197  Keywords:  Adult, Animals, Brain:drug effects, Cells, Cultured, Clozapine:pharmacology, Dopamine:pharmacology, Dopamine Antagonists:pharmacology, Dose-Response Relationship, Drug, Female, Haloperidol:pharmacology, Humans, Interferon-gamma:metabolism, Interleukin-10:.    Citation

OBJECTIVES: Dopamine (DA) administration in sepsis is used to modulate the hypotensive condition and to normalize the blood vessels perfus.....

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Epicatechin suppresses IL-6, IL-8 and enhances IL-10 production with NF-kappaB nuclear translocation in whole blood stimulated system.

Al-Hanbali M, Ali D, Bustami M, Abdel-Malek S, Al-Hanbali R, Alhussainy T, Qadan F, Matalka K.

Journal Article 2009; 30(1): 131-138 PubMed PMID: 19300393  Keywords:  Adult, Blood Cells:drug effects, Catechin:pharmacology, Cell Culture Techniques, Cell Nucleus:drug effects, Cell Proliferation:drug effects, Cells, Cultured, Drug Evaluation, Preclinical, Female, Humans, Interleukin-10:blood, Interleukin-6:blood, Interleu.    Citation

OBJECTIVES: Cytokines induce the balance between inflammatory versus regulatory or antibody mediated reactions. So modulating the release .....

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Measurement of protein cytokines in tissue extracts by enzyme-linked immunosorbent assays: application to lipopolysaccharide-induced differential milieu of cytokines.

Matalka K, Tutunji M, Abu-Baker M, Abu Baker Y.

Journal Article 2005; 26(3): 231-236 PubMed PMID: 15990727  Keywords:  Animals, Brain Chemistry:immunology, Cell Extracts:chemistry, Cytokines:analysis, Detergents, Enzyme-Linked Immunosorbent Assay:methods, Interferon-gamma:analysis, Interleukin-10:analysis, Kidney:chemistry, Lipopolysaccharides:pharmacology, Liver:chemistr.    Citation

OBJECTIVES: Determination of protein cytokines in local tissues would help to evaluate their local role in health, sickness behavior and i.....

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Neuroendocrine and cytokines-induced responses to minutes, hours, and days of mental stress.

Matalka K.

Journal Article 2003; 24(5): 283-292 PubMed PMID: 14646999  Keywords:  Cytokines:physiology, Humans, Neuroimmunomodulation:physiology, Neurosecretory Systems:immunology, Stress, Psychological:immunology, Time Factors,.    Citation

OBJECTIVES: Previously, a large number of studies reported that psychological stress and psychiatric illness reduces immune responsiveness.....

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The effect of estradiol, but not progesterone, on the production of cytokines in stimulated whole blood, is concentration-dependent.

Matalka K.

Journal Article 2003; 24(3-4): 185-191 PubMed PMID: 14523355  Keywords:  Cytokines:biosynthesis, Dose-Response Relationship, Drug, Estradiol:pharmacology, Female, Humans, Hydrocortisone:antagonists & inhibitors, In Vitro Techniques, Indicators and Reagents, Interferon-gamma:biosynthesis, Interleukin-10:biosynthesis, Interleuki.    Citation

OBJECTIVES: The purpose of this study was to determine the effects of estradiol and progesterone on interferon-gamma (IFN-gamma), interleu.....

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