Mammary invasive ductal adenocarcinoma and vulvar invasive keratinizing squamous cell carcinoma in a woman with disseminated discoid lupus erythematosus (DDLE) - a case review.

: A case of metachronous presentation of two malignancies, invasive mammary ductal adenocarcinoma and later invasive keratinizing squamous cell vulvar carcinoma, complicating a 20 years long course of disseminated discoid lupus erythematosus is described. The authors underline a potential role of long-standing immunotherapy as a factor responsible for inducing secondary neoplasia.