Articles by author - Frantisek Drafi

Ascorbate and Cu(II)-induced oxidative degradation of high-molar-mass hyaluronan. Pro- and antioxidative effects of some thiols.

Valachova K, Hrabarova E, Drafi F, Juranek I, Bauerova K, Priesolova E, Nagy M, Soltes L.

Journal Article 2010; 31(Suppl 2): 101-104 PubMed PMID: 21187839  Keywords:  Antioxidants:pharmacology, Ascorbic Acid:pharmacology, Copper:pharmacology, Cysteamine:pharmacology, Dose-Response Relationship, Drug, Glutathione:pharmacology, Hyaluronic Acid:metabolism, Hydrogen Peroxide:metabolism, Hydroxides:metabolism, Oxidation-Red.    Citation

OBJECTIVE: This study presents the results of antioxidative and pro-oxidative efficacy of cysteamine and D-penicillamine (D-pen) in compar.....

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Carnosine inhibits degradation of hyaluronan induced by free radical processes in vitro and improves the redox imbalance in adjuvant arthritis in vivo.

Drafi F, Bauerova K, Valachova K, Ponist S, Mihalova D, Juranek I, Boldyrev A, Hrabarova E, Soltes L.

Journal Article 2010; 31(Suppl 2): 96-100 PubMed PMID: 21187837  Keywords:  Animals, Antioxidants:pharmacology, Antirheumatic Agents:pharmacology, Arthritis, Experimental:drug therapy, Carnosine:pharmacology, Disease Models, Animal, Free Radicals, Glutathione:metabolism, Hyaluronic Acid:metabolism, In Vitro Techniques, Male, Meth.    Citation

OBJECTIVE: New ways of supplementary or combinatory therapy of rheumatoid arthritis (RA) are of great importance. The aim is to find an ad.....

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