Vol. 39 (3) 2018 Neuro endocrinology letters

Coexistence of neurofibromatosis type 1 with multiple malignant neoplasia.

: Neurofibromatosis type 1 (NF1, von Recklinghausen disease) is inherited in autosomal dominant way genetic disorder, with an incidence at birth 1:3000. It is one of the most common congenital disorders. It is characterized by café-au-lait spots, neurofibromas, and less common MPTST and gliomas of the optic nerve. It is caused by germl.....