Expression of Ki-67, p53 and vascular endothelial growth factor (VEGF) concomitantly in growth hormone-secreting pituitary adenomas; which one has a role in tumor behavior ?

Yarman S, Kurtulmus N, Canbolat A, Bayindir C, Bilgic B, Ince N.

Journal Article 2010; 31(6): 823-828 PubMed PMID: 21196926 Keywords: Acromegaly:etiology, Adenoma:complications, Adult, Aged, Biomarkers, Tumor:metabolism, Early Diagnosis, Female, Growth Hormone-Secreting Pituitary Adenoma:complications, Humans, Immunohistochemistry, Ki-67 Antigen:metabolism, Male, Middle Aged, Neoplasm I.

OBJECTIVE: In many pituitary tumor, immunohistochemical studies have been shown to be correlated with different aspects of tumor behavior.There is no study up to date in which markers of Ki-67, p53, VEGF were evaluated concomitantly in GH-secreting adenomas.This study aims to determine which marker has a major role in tumor behavior and.....

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Vol. 31 (6) 2010 Neuro endocrinology letters

Expression of Ki-67, p53 and vascular endothelial growth factor (VEGF) concomitantly in growth hormone-secreting pituitary adenomas; which one has a role in tumor behavior ?

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