Vol. 28 (4) 2007 Neuro endocrinology letters

Single base substitution in growth hormone receptor gene influences the receptor density in bovine liver.

OBJECTIVES: Nucleotide sequence polymorphisms in the coding gene regions may influence the biological properties of proteins encoded by a gene. The A/T substitution in exon 8 of the growth hormone receptor (GHR) gene results in changed amino acid sequence 279 (Phe/Tyr) in the transmembrane domain of the receptor protein and therefore co.....