Vol. 28 (4) 2007 Neuro endocrinology letters

Investigation of V600E BRAF mutation in papillary thyroid carcinoma in the Polish population.

UNLABELLED: Papillary thyroid carcinoma (PTC) is the most common malignancy of the thyroid gland. The high incidence of RET/PTC and Trk rearrangements or point mutations in RAS and c-MET oncogenes are the genetic hallmarks of PTC. Recently, oncogene BRAF has become a subject of great interest. The mutation of BRAF gene is characteristic.....