Vol. 25 (3) 2004 Neuro endocrinology letters

Effect of bromocriptine on cell apoptosis and proliferation in GH3 cell culture.

OBJECTIVES: In our study, with the use of GH3 cells line we decided to examine 1) what is the relation between the dose of bromocriptine and the development of apoptosis in GH3 cells 2) whether the induction of apoptosis is accompanied by alterations in bcl-2 and p53 content and 3) whether dibutyryl-cAMP or phorbol esters affect the ini.....