Vol. 25 (1-2) 2004 Neuro endocrinology letters

Glucocorticoid-dependency of increased adiposity in a model of hypothalamic obesity.

UNLABELLED: It is known that rats treated, at neonatal age, with monosodium L-glutamate (MSG) develop neuroendocrine and metabolic abnormalities, resulting in a phenotype of hypothalamic obesity, characterized by increased adiposity, corticosteronemia and leptinemia.

OBJECTIVE: We explored whether adrenal manipul.....