Light during darkness, melatonin suppression and cancer progression.
: Over the past few years, we have shown that the surge of melatonin in the circulation during darkness represents a potent oncostatic signal to tissue-isolated rat hepatoma 7288CTC, which is an ER+ adenocarcinoma of the liver. This oncostatic effect occurs via a melatonin receptor-mediated suppression of tumor cAMP production that lead.....
Citation
Portier C. Comments on the International Symposium on Light, Endocrine Systems and Cancer. Neuro Endocrinol Lett. 2002 Jul; 23(Suppl 2): 79-81