Are abnormalities in lipid metabolism, together with adverse childhood experiences, the silent causes of immune-linked neurotoxicity in major depression?

Journal Article 2024; 45(6): 393-408 PubMed PMID: 39732467

BACKGROUND: Severe or recurring major depression is associated with increased adverse childhood experiences (ACEs), heightened atherogenic.....

First-episode mild depression in young adults is a pre-proatherogenic condition even in the absence of subclinical metabolic syndrome: lowered lecithin-cholesterol acyltransferase as a key factor.

Journal Article 2024; 45(7-8): 475-491 PubMed PMID: 39737498

BACKGROUND: Major depression is classified into distinct subtypes: simple (SDMD) and major dysmood disorder (MDMD). MDMD patients exhibit .....

Journal Article 2025; 46(5): 295-302 PubMed PMID: 41337649

INTRODUCTION: Pituitary adenomas are the primary cause of Cushing's disease (CD), yet they can produce negative MRI findings when coexisti.....

Journal Article 2025; 46(6): 315-322 PubMed PMID: 41420879

BACKGROUND: Autism Spectrum Disorder (ASD) is a neurodevelopmental condition that impairs communication. Increasing research indicates tha.....

Journal Article 2026; 47(1): 29-36 PubMed PMID: 41915925 Keywords: Humans, Glioblastoma:genetics, Mendelian Randomization Analysis, Hypothyroidism:genetics, Polymorphism, Single Nucleotide, Genome-Wide Association Study, Brain Neoplasms:genetics, Genetic Predisposition to Disease, Risk Factors,.

BACKGROUND: Prior observational evidence suggests a potential link between hypothyroidism and glioblastoma (GBM) risk. To investigate caus.....