OBJECTIVES: Since there are clear indications that schizophrenia is a systemic disorder, we sought for a common molecular basis for schizo.....
Melkersson K, Persson B. Evidence for a negative association between schizophrenia and a polymorphism in the insulin receptor substrate-3 (IRS-3) gene. Neuro Endocrinol Lett. 2012 Jan; 33(3): 321-330
OBJECTIVES: The insulin receptor substrate-4 (IRS-4) protein is highly expressed in the hypothalamus that plays a main role in the regulat.....
Melkersson K, Persson B. Association between body mass index and insulin receptor substrate-4 (IRS-4) gene polymorphisms in patients with schizophrenia. Neuro Endocrinol Lett. 2011 Jan; 32(5): 634-640
Melkersson K, Persson B, Hongslo T.
Journal Article 2011; 32(1): 52-58 PubMed PMID: 21407155 Keywords: Adult, Case-Control Studies, Female, Genetic Predisposition to Disease, Haplotypes, Humans, Insulin Receptor Substrate Proteins:genetics, Male, Middle Aged, Point Mutation, Polymorphism, Single Nucleotide, Schizophrenia:genetics,. CitationOBJECTIVES: Since there are clear indications that schizophrenia is a systemic disorder, we sought for a common molecular basis for schizo.....
Melkersson K, Persson B, Hongslo T. The insulin receptor substrate-4 (IRS-4) gene and schizophrenia: no evidence for a main genetic factor, however one report of a single schizophrenia patient with a mutation. Neuro Endocrinol Lett. 2011 Jan; 32(1): 52-58
OBJECTIVES: Schizophrenia is a psychotic disorder with high heritability. There are also indications that impaired cellular signalling via.....
Melkersson K, Persson B. Association between single nucleotide polymorphisms in non-coding regions of the insulin (INS) gene and schizophrenia. Neuro Endocrinol Lett. 2022 Apr; 43(1): 1-8
OBJECTIVES: Schizophrenia is a psychotic disorder with high heritability. There are also indications that an autoimmune-mediated process i.....
Melkersson K, Persson B. Associations between heredity, height, BMI, diabetes mellitus type 1 or 2 and gene variants in the insulin receptor (INSR) gene in patients with schizophrenia. Neuro Endocrinol Lett. 2023 Mar; 44(1): 39-54