Articles by author - Magdalena Kochman

Different signaling in pig anterior pituitary cells by GnRH and its complexes with copper and nickel.

Kochman K, Blitek A, Kaczmarek M, Gajewska A, Siawrys G, Counis R, Ziecik A.

Journal Article 2005; 26(4): 377-382 PubMed PMID: 16136005  Keywords:  Animals, Copper:metabolism, Cyclic AMP:metabolism, Female, Gonadotropin-Releasing Hormone:metabolism, Hydrolysis, Inositol Phosphates:metabolism, Luteinizing Hormone:secretion, Nickel:metabolism, Phosphatidylinositols:metabolism, Pituitary Gland, Anterior.    Citation

: Gonadotropin releasing hormone (GnRH) is an essential factor in the regulation of synthesis and release of pituitary gonadotropins. Afte.....

Read abstract  Full text PDF

Further structural analysis of GnRH complexes with metal ions.

Nakamura K, Kodaka M, El-Mehasseb I, Gajewska A, Okuno H, Ochwanowska E, Witek B, Kozłowski H, Kochman K.

Journal Article 2005; 26(3): 247-252 PubMed PMID: 15990730  Keywords:  Animals, Copper:chemistry, Gonadotropin-Releasing Hormone:chemistry, Metals, Heavy:chemistry, Nickel:chemistry, Nuclear Magnetic Resonance, Biomolecular, Protons, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization,.    Citation

: MALDI-TOF mass spectrometry, 1H NMR spectrometry, the continuous variation method and molecular modeling by MM3 calculation confirmed ou.....

Read abstract  Full text PDF

Leptin gene expression in the hypothalamus and pituitary of pregnant pigs.

Smolinska N, Przala J, Kaminski T, Siawrys G, Gajewska A, Kochman K, Okrasa S.

Journal Article 2004; 25(3): 191-195 PubMed PMID: 15349084  Keywords:  Animals, Base Sequence, DNA Primers, Female, Gene Expression Regulation, Hypothalamus:physiology, Leptin:genetics, Pituitary Gland:physiology, Polymerase Chain Reaction, Pregnancy, Pregnancy, Animal:physiology, RNA, Messenger:genetics, Swine,.    Citation

BACKGROUND: Leptin, the 16-kDa peptide hormone product of the ob gene, is a regulatory hormone secreted mainly by adipose tissue. Recent s.....

Read abstract

Impaired somatostatin accumulation within the median eminence in mice with mosaic mutation.

Wojewodzka U, Gajewska A, Gajkowska B, Styrna J, Kochman K.

Comparative Study 2004; 25(1-2): 78-82 PubMed PMID: 15159688  Keywords:  Adenosine Triphosphatases:genetics, Animals, Cation Transport Proteins:genetics, Copper:deficiency, Disease Models, Animal, Female, Male, Median Eminence:diagnostic imaging, Menkes Kinky Hair Syndrome:genetics, Mice, Mice, Mutant Strains, Mutation, Recomb.    Citation

OBJECTIVES: The mosaic mutation (Atp7a(mo-ms)) linked to X-chromosome is caused by changes in the Atp7a gene encoding CPx-type protein res.....

Read abstract  Full text PDF

GnRH pulsality and the differential activation of the rat luteinizing hormone subunit genes in the anterior pituitary gland.

Gajewska A, Kochman K.

Journal Article 2001; 22(6): 435-440 PubMed PMID: 11781541  Keywords:  Animals, Gene Expression:physiology, Gonadotropin-Releasing Hormone:metabolism, Luteinizing Hormone:genetics, Pituitary Gland, Anterior:physiology,.    Citation

: Detailed studies have been focused on the mechanisms by which the rat alpha and LHbeta genes are differentially regulated by GnRH and in.....

Read abstract