Articles by author - Vladimir Holec

Study of the APC gene function in the mouse APC+/APC1638N model.

Adamcikova Z, Wachsmannova L, Hainova K, Stevurkova V, Holec V, Ciernikova S, Cierna Z, Janega P, Babal P, Mego M, Zajac V.

Journal Article 2012; 33(1): 26-33 PubMed PMID: 22467108  Keywords:  Adenomatous Polyposis Coli, Animals, Disease Models, Animal, Genes, APC, Germ-Line Mutation, Mice, Mutation, Phenotype,.    Citation

OBJECTIVES: Familial adenomatous polyposis (FAP) is an autosomal dominant disease characterized by the presence of hundreds to thousands o.....

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Polymorphisms in the adenomatous polyposis coli gene in Slovak families suspected of FAP.

Wachsmannova-Matelova L, Stevurkova V, Adamcikova Z, Holec V, Zajac V.

Journal Article 2009; 30(Suppl 1): 25-28 PubMed PMID: 20027139  Keywords:  Adenomatous Polyposis Coli:genetics, Cohort Studies, Exons, Family, Genes, APC, Genetic Predisposition to Disease, Humans, Mutation, Polymorphism, Genetic, Polymorphism, Single-Stranded Conformational, Sequence Analysis, DNA, Slovakia,.    Citation

OBJECTIVES: Polymorphism in the adenomatous polyposis coli (APC) gene was analyzed in 33 families suspected of familial adenomatous polypo.....

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