Stara V, Navarova J, Ujhazy E, Gasparova Z.
Journal Article 2016; 37(Suppl 1): 111-117 PubMed PMID: 28263538 Keywords: Animals, Disease Models, Animal, Evoked Potentials, Hippocampus:drug effects, Lysosomes:drug effects, Male, Neurodegenerative Diseases:chemically induced, Neurons:physiology, Rats, Rats, Wistar, Trimethyltin Compounds:administration & dosage,. CitationOBJECTIVES: Extensive effort has been made to identify early markers of neurodegeneration as late stages have no chance of treatm.....
Stara V, Navarova J, Ujhazy E, Gasparova Z. Progressive increase of lysosomal enzyme activities in hippocampus associated with reduction of population spike in a rat model of neurodegeneration. Neuro Endocrinol Lett. 2016 Dec; 37(Suppl 1): 111-117
Gasparova Z, Stara V, Janega P, Navarova J, Sedlackova N, Mach M, Ujhazy E.
Journal Article 2014; 35(6): 454-462 PubMed PMID: 25433849 Keywords: Acetylglucosaminidase:metabolism, Alzheimer Disease:drug therapy, Animals, Antioxidants:pharmacology, CA1 Region, Hippocampal:drug effects, Cognition Disorders:drug therapy, Disease Models, Animal, Indoles:pharmacology, Male, Malondialdehyde:metabolism, M. CitationBACKGROUND: The idea of antioxidant therapy attenuating Alzheimer disease (AD) neuropathology starts to be attractive. Animal models are o.....
Gasparova Z, Stara V, Janega P, Navarova J, Sedlackova N, Mach M, Ujhazy E. Pyridoindole antioxidant-induced preservation of rat hippocampal pyramidal cell number linked with reduction of oxidative stress yet without influence on cognitive deterioration in Alzheimer-like neurodegeneration. Neuro Endocrinol Lett. 2014 Jan; 35(6): 454-462
Gasparova Z, Janega P, Stara V, Ujhazy E.
Journal Article 2012; 33(7): 689-696 PubMed PMID: 23391880 Keywords: Animals, CA1 Region, Hippocampal:pathology, Cerebral Cortex:pathology, Disease Models, Animal, Disease Progression, Excitatory Postsynaptic Potentials:drug effects, Male, Neurodegenerative Diseases:chemically induced, Neurotoxins:toxicity, Rats, Rats, Wis. CitationBACKGROUND: Trimethyltin (TMT), a potent neurotoxicant, elicits neuronal death in the limbic system and causes damage particularly in the .....
Gasparova Z, Janega P, Stara V, Ujhazy E. Early and late stage of neurodegeneration induced by trimethyltin in hippocampus and cortex of male Wistar rats. Neuro Endocrinol Lett. 2012 Jan; 33(7): 689-696
Gáspárová Z, Snirc V, Stolc S, Dubovický M, Mach M, Ujházy E.
Journal Article 2010; 31(3): 348-352 PubMed PMID: 20588238 Keywords: Action Potentials:drug effects, Animals, Antioxidants:therapeutic use, Brain Ischemia:prevention & control, Female, Hippocampus:drug effects, In Vitro Techniques, Indoles:therapeutic use, Lactation, Pregnancy, Pregnancy Complications, Cardiovascular:drug . CitationOBJECTIVE: Damage to the developing brain may be caused by maternal environment, nutritional deficiencies, failure of protective mechanism.....
Gáspárová Z, Snirc V, Stolc S, Dubovický M, Mach M, Ujházy E. Maternal treatment of rats with the new pyridoindole antioxidant during pregnacy and lactation resulting in improved offspring hippocampal resistance to ischemia in vitro. Neuro Endocrinol Lett. 2010 Jan; 31(3): 348-352
Gáspárová Z, Janega P, Babál P, Snirc V, Stolc S, Mach M, Ujházy E.
Journal Article 2009; 30(5): 574-581 PubMed PMID: 20035262 Keywords: Animals, Antioxidants:pharmacology, Brain Ischemia:drug therapy, Edema:drug therapy, Electrophysiology, Female, Hippocampus:cytology, Humans, Indoles:pharmacology, Male, Neuroprotective Agents:pharmacology, Pyridines:pharmacology, Rats, Rats, Wistar,. CitationOBJECTIVES: The idea of neuroprotective therapy for ischaemic stroke is based on results from studies on experimental animal models of bra.....
Gáspárová Z, Janega P, Babál P, Snirc V, Stolc S, Mach M, Ujházy E. Effect of the new pyridoindole antioxidant SMe1EC2 on functional deficits and oedema formation in rat hippocampus exposed to ischaemia in vitro. Neuro Endocrinol Lett. 2009 Jan; 30(5): 574-581
Gasparova Z, Jariabka P, Stolc S.
Journal Article 2008; 29(5): 702-705 PubMed PMID: 18987602 Keywords: Animals, Electric Stimulation, Excitatory Postsynaptic Potentials:physiology, Hippocampus:blood supply, Ischemic Attack, Transient:physiopathology, Long-Term Potentiation:physiology, Male, Rats, Rats, Wistar, Synaptic Transmission:physiology,. CitationOBJECTIVES: Long-term potentiation (LTP) of neuronal activity in the hippocampus is thought to be a substrate for learning and memory. The.....
Gasparova Z, Jariabka P, Stolc S. Effect of transient ischemia on long-term potentiation of synaptic transmission in rat hippocampal slices. Neuro Endocrinol Lett. 2008 Oct; 29(5): 702-705