: Emil Starkenstein (1884-1942), professor of pharmacology at the German Medical Faculty of Charles University in Prague, was not only an experimental pharmacologist, but also the pioneer of clinical pharmacology. During the World War I (1914-1918) he took advantage of his knowledge of experimental pharmacology for the new approaches to the treatment of bacillary dysentery, cholera and of epidemic typhus fever. In 1918 he published the article "Clinical Pharmacology--Theory and Praxis at the Patient's Bedside", in which he defined the main task of clinical pharmacology as the implementation and verification of experimental pharmacology achievements in clinical therapy. During the period 1921-1933, his scientific interests involved namely analgesic combinations, seasickness therapy and pharmacology of iron. He published more than 240 scientific articles and three textbooks. Emil Starkenstein died on November 6, 1942 as a victim of Holocaust. Starkenstein s collection of more than 20,000 reprints of scientific studies, which has been deposited recently in the Archives of Charles University in Prague is very valuable.