Controversial opinions on the role of cocaine and amphetamine-regulated transcript (CART) in prolactin release.

: Cocaine and amphetamine regulated transcript (CART) is widely expressed in the central nervous system and in several endocrine organs. The physiological role of this peptide includes modulation of appetite control, energy expenditure, thermoregulation and hormone secretion. It has been suggested that CART influences prolactin (PRL) secretion both directly and indirectly. However, the mechanism underlying the regulation of PRL release by CART remains unclear.

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