Acquired generalized lipodystrophy in a young lean Chinese girl. Case Report.

  Vol. 36 (7) 2015 Neuro endocrinology letters Journal Article   2015; 36(7): 650-652 PubMed PMID:  26859586    Citation

: Lipodystrophies is a really rare group of diseases characterized by altered body fat amount and/or repartition and serious insulin resistance.We reported a lean Chinese girl with acquired generalized lipodystrophy, who had a long history of poorly controlled diabetes mellitus (DM) despite with extremely high dose insulin (6 u/kg/d) therapy, combined with severe hypertriglyceridemia and acanthosis nigricans. The differential diagnosis of Lipodystrophies should be considered in lean patients presenting with early onset DM, combined with serious insulin resistance.

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