Vol. 44 (1) 2023 Neuro endocrinology letters

The effect of sinomenine on ERK1/2, JNK and p38 phosphorylation in LPS-stimulated endothelial cells.

: This study was to investigate the effect of sinomenine by LPS-induced MAPK phosphorylation in endothelial cells. Endothelial cells were challenged with different doses LPS and/or treated with sinomenine at three concentrations (1, 5, or 10 μg/mL) in pathological model, drug safety, treatment and prevention experiments. The cells were.....