ATG16L1 regulated IL-22 induced IFN level in Pseudomonas aeruginosa Lung Infection via cGAS signal passage.
OBJECTIVE: This study explored that the possible effects and mechanism of ATG16L1 in pseudomonas aeruginosa lung infection. METHODS: C57BL/6J mice were anesthetized with isoflurane and intratracheally (I.T.) inoculated with 5 × 106 CFU of Pseudomonas aeruginosa strain PA14. RAW264.7 macrophages were stimu.....