Vol. 42 (2) 2021 Neuro endocrinology letters

Eicosapentaenoic acid attenuates Aβ-induced neurotoxicity by decreasing neuroinflammation through regulation of microglial polarization.

OBJECTIVE: Although the cause of Alzheimer's disease (AD) is still controversial, it is generally accepted that neuroinflammation plays a key role in AD pathogenesis. Thus, regulating the polarization of microglia will help in recovering from AD since microglia can be polarized into classical M1 and alternative M2 phenotypes, M.....