Vol. 41 (2) 2020 Neuro endocrinology letters

The metabolic, neuroprotective cardioprotective and antitumor effects of the Klotho protein.

: Klotho is a transmembrane protein with a wide spectrum of activity. The human Klotho gene shows 86% amino acid identity with the mouse protein. Many important pleiotropic functions of the Klotho protein have been revealed. Amongst them, there is a regulation of nitric oxide production, suppression of oxidative stress and inf.....