Vol. 41 (1) 2020 Neuroendocrinol Lett

Neurofilament light chain and MRI volume parameters as markers of neurodegeneration in multiple sclerosis

BACKGROUND: Neurofilament light chain (NfL) is considered a major marker of neurodegeneration and disease activity. Higher levels of NfL are associated with worse clinical outcomes and increased brain atrophy. In treated patients with Relapsing-Remitting Multiple Sclerosis (RRMS), we aimed to determine the level of NfL, an assoc.....