Vol. 36 (4) 2015 Neuro endocrinology letters

Sonic hedgehog overexpression regulates the neuroepithelial cells proliferation in the spinal cord of dorsal regions during chicken embryo development.

OBJECTIVE: Sonic hedgehog(SHH) is early expressed in the floor plate and notochord during the development of chicken embryo, which is required for the establishment of dorsal axis and the formation of spinal cord, but the mechanism of SHH affecting the patterns of spinal development is still unclear.

METHODS: In .....