Vol. 36 (2) 2015 Neuro endocrinology letters

Environmental enrichment increases PACAP levels in the CNS of adult rats.

OBJECTIVE: Pituitary adenylate cyclase activating polypeptide (PACAP) is a pleiotropic and multifunctional neuropeptide, widely distributed throughout the body. It is involved in the regulation of various physiological and pathophysiological processes. Numerous studies have shown that PACAP is involved in the development of the central .....