Vol. 35 (Suppl 2) 2014 Neuro endocrinology letters

The impact of clozapine on regulation of inflammation in murine macrophage cells.

OBJECTIVES: Clozapine is an atypical antipsychotic drug known for its impact on production of pro-inflammatory cytokines. The aim of our work was to examine the impact of clozapine on the production of interleukin 6 (IL-6) by the LPS (lipopolysaccharide) stimulated macrophage cells and to confirm or exclude that it regulates th.....