Vol. 34 (5) 2013 Neuro endocrinology letters

4,5-dianilinophtalimide protects neuroendocrine cells against serum deprivation-induced stress and apoptosis.

OBJECTIVE: The aim of this study was to reveal the effects of 4,5-dianilinophthalimide (DAPH), which inhibits amyloid β fibrillization, against serum deprivation (SD)-induced apoptosis and the possible mechanisms in differentiated PC12 neuron cells.

METHODS: Firstly, we evaluated whether DAPH protects cell viabi.....