Vol. 34 (1) 2013 Neuro endocrinology letters

Cerebrospinal fluid concentrations of ghrelin in patients with multiple sclerosis.

: Ghrelin, an orexigenic peptide, exerts immunomodulatory and other effects in the CNS and has neuroprotective properties. Ghrelin is predominantly produced by X/A-like cells in the gastric mucosa. Hence, ghrelin's main source of production lies outside the CNS while important functions of ghrelin are operated by specific receptors in t.....