Vol. 31 (5) 2010 Neuro endocrinology letters

Expression and distribution of P450-aromatase in the ovine hypothalamus at different stages of fetal development.

OBJECTIVES: An important step of sexual differentiation is the conversion of testosterone to estrogen by aromatase leading to masculinization and defeminization of the fetal brain areas crucial for normal sexual behavior and reproduction. Brain sexual differentiation occurs throughout a critical period starting from different prenatal s.....