Oxytocin and carbetocin ameliorating effects on restraint stress-induced short- and long-term behavioral changes in rats.

Klenerova V, Krejci I, Sida P, Hlinak Z, Hynie S.

Journal Article 2010; 31(5): 622-630 PubMed PMID: 21173744 Keywords: Animals, Anxiety:drug therapy, Behavior, Animal:drug effects, Delayed-Action Preparations:administration & dosage, Injections, Intraperitoneal, Locomotion:drug effects, Male, Maze Learning:drug effects, Motor Activity:drug effects, Oxytocics:administratio.

OBJECTIVES: Carbetocin (CBT), an oxytocin (OXY) analog, was designed to exert prolonged peripheral actions. It has also been proposed as potential therapeutic mean in certain psychiatric disorders where OXY role has been implicated. This study examined the effects of both peptides on behavior of naive and restraint stress exposed rats i.....

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Vol. 31 (5) 2010 Neuro endocrinology letters

Oxytocin and carbetocin ameliorating effects on restraint stress-induced short- and long-term behavioral changes in rats.

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